内科胸腔镜诊断胸腹腔积液合并CA125升高的卵巢颗粒细胞瘤一例并文献复习  

A Case of Ovarian Granulosa Cell Tumor with Pleural Effusion and Ascites Combined with Elevated CA125 Diagnosed by Medical Thoracoscopy and Literature Review

作　　者：李官红 郑玉琼[1] 李文[1] 谢盛 王慧[1] LI Guanhong;ZHENG Yuqiong;LI Wen;XIE Sheng;WANG Hui(Chengdu Integrated Traditional Chinese and Western Medicine Hospital,Chengdu 610041,China)

机构地区：[1]成都市中西医结合医院,四川成都610041

出　　处：《中国医学创新》2021年第22期166-170,共5页Medical Innovation of China

摘　　要：卵巢颗粒细胞瘤(ovarian granulosa cell tumor,OGCT)是卵巢性索间质细胞瘤中最常见的一种恶性肿瘤,占全部卵巢肿瘤的2%~5%。OGCT有内分泌功能,临床上常表现为月经紊乱、阴道不规则出血、性早熟等雌激素刺激症状,腹部包块是OGCT的另一个较常见症状。由于OGCT发病率低,且缺乏典型临床症状,临床工作中容易被误诊、漏诊。本文报道1例通过内科胸腔镜诊断的胸腹腔积液合并CA125升高的OGCT,并进行文献复习,以期提高临床医师对该疾病的认识。Ovarian granulosa cell tumor (OGCT) is the most common malignant tumor among ovarian sex cord stromal cell tumors,accounting for 2% to 5% of all ovarian tumors.OGCT has endocrine function,which is often clinically manifested as menstrual disorder,irregular vaginal bleeding,precocious puberty and other estrogen stimulation symptoms.Abdominal mass is another common symptom of OGCT.Due to the low incidence of OGCT and the lack of typical clinical symptoms,it is easy to be misdiagnosed and missed diagnosis in clinical work.In this paper,we report a case of OGCT with pleural effusion and ascites combined with elevated CA125 diagnosed by medical thoracoscopy,and review the literature in order to improve clinicians’ understanding of this disease.

关 键 词：卵巢颗粒细胞瘤 胸腹腔积液 CA125 内科胸腔镜 

分 类 号：R737.31[医药卫生—肿瘤]