局部热疗联合医用放疗皮肤防护剂对乳腺癌术后胸壁放疗急性放射性皮肤损伤的疗效观察  

Effect of Local Hyperthermia Combined with Skin Protective Agent of Medical Radiotherapy on Acute Radiation Skin Damage of Breast Cancer Postoperative Chest Wall Radiation Therapy

作　　者：丁学锋 魏旭升 严晓花 温鹏军 谢洪霞 毛宏亮[1] DING Xuefeng;WEI Xusheng;YAN Xiaohua;WEN Pengjun;XIE Hongxia;MAO Hongliang(Jiuquan City People’s Hospital,Jiuquan 735000,China)

机构地区：[1]甘肃省酒泉市人民医院,甘肃酒泉735000

出　　处：《中国医学创新》2021年第25期171-175,共5页Medical Innovation of China

摘　　要：目的:探讨局部热疗联合医用放疗皮肤防护剂对乳腺癌术后胸壁放疗急性放射性皮肤损伤的疗效。方法:选取2018年2月-2020年2月本院60例行乳腺癌术后胸壁放疗期间发生的急性放射性皮肤损伤患者,按照随机数字表法将其分为观察组和对照组,每组30例。对照组涂抹医用放疗皮肤防护剂治疗,观察组在对照组的基础上进行局部热疗。比较两组放疗结束时皮肤损伤分级、急性放射性皮肤损伤治疗效果,比较两组瘙痒缓解时间、疼痛缓解时间、皮肤愈合时间,比较两组治疗前后的SF-36评分。结果:观察组皮肤损伤0、1级所占比例均高于对照组,差异均有统计学意义(P<0.05)。两组2、3、4级所占比例比较,差异均无统计学意义(P>0.05)。观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组瘙痒缓解时间、疼痛缓解时间及皮肤愈合时间均短于对照组,差异均有统计学意义(P<0.05)。治疗前,两组躯体功能、社会功能、生理功能、健康状况、精神健康、精力状态、情感职能、生理职能评分比较,差异均无统计学意义(P>0.05);治疗后,观察组躯体功能、社会功能、生理功能、健康状况、精神健康、精力状态、情感职能、生理职能评分均高于对照组,差异均有统计学意义(P<0.05)。结论:局部热疗联合医用放疗皮肤防护剂能够提高乳腺癌术后胸壁放疗急性放射性皮肤损伤的疗效,缓解皮肤症状,缩短愈合时间,提高生活质量,值得临床推荐。Objective:To explore effect of local hyperthermia combined with skin protective agent of medical radiotherapy on acute radiation skin injury of breast cancer postoperative chest wall radiation therapy.Method:A total of 60 patients with acute radiation skin damage after postoperative chest wall radiation therapy for breast cancer in our hospital from February 2018 to February 2020 were selected,and they were divided into observation group and control group according to random number table method,30 cases in each group.The control group was treated with skin protective agent of medical radiotherapy,and the observation group was treated with local hyperthermia on the basis of the control group.The skin damage grade at the end of radiotherapy and the treatment effect of acute radiation skin damage were compared between the two groups,the itch relief time,pain relief time and skin healing time were compared between two groups,and the SF-36 score before and after treatment was compared between two groups.Result:The proportions of grade 0 and grade 1 skin damage in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).There were no significant differences in the proportion of grade 2,3 and 4 between two groups (P>0.05).The total effective rate in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05).The itch relief time,pain relief time and skin healing time in the observation group were shorter than those in the control group,and the differences were statistically significant (P<0.05).Before treatment,there was no significant differences in the scores of physical function,social function,physiological function,health status,mental health,energy status,emotional function and physiological function between two groups (P>0.05);after treatment,the scores of physical function,social function,physiological function,health status,mental health,energy status,emotional function and physiolo

关 键 词：乳腺癌 术后胸壁放疗 急性放射性皮肤损伤 局部热疗 

分 类 号：R737.9[医药卫生—肿瘤]