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作 者:林楠[1] 刘丽[1] 田洁[1] 雷晓军 扈月平[1] LIN Nan;LIU Li;TIAN Jie;LEI Xiao-jun;HU Yue-ping(Department of Ophthalmology,Dalian Friendship Hospital,Liaoning Province,Dalian116001,China)
出 处:《中国当代医药》2021年第26期188-190,194,共4页China Modern Medicine
基 金:辽宁省大连市医学科学研究计划项目(1911061)。
摘 要:目的对特发性黄斑前膜(IMEM)黄斑微结构变化与眼部视觉及色觉进行相关性分析。方法选取2019年1月至2021年1月大连市友谊医院眼科收治的30例单眼IMEM患者(60只眼)作为研究对象,按照是否为IMEM患眼分为IMEM眼组和对照组,每组各30只眼。观察两组的最佳矫正视力(BCVA),采用Farnsworth Munsell 100 Hue色觉测试系统(FM 100 Hue Test)进行色觉检查,采用频域光相干断层扫描(SD-OCT)检查黄斑中心凹厚度(CFT),观察黄斑区椭圆体带(EZ)连续性并进行统计学分析。结果IMEM眼组的BCVA低于对照组,色觉得分高于对照组,CFT厚于对照组,差异有统计学意义(P<0.05)。EZ连续性完整的BCVA高于EZ连续性中断,色觉得分低于EZ连续性中断,差异均有统计学意义(P<0.05)。CFT和IMEM分级与BCVA和色觉得分呈正相关(P<0.05),年龄与色觉得分呈正相关(P<0.05)。结论年龄越大,特发性黄斑前膜分级越高,黄斑中心凹厚越厚,最佳矫正视力及色觉越差;特发性黄斑前膜病例中,椭圆体带连续病例的最佳矫正视力及色觉好于椭圆体带中断病例。Objective To analyze the correlation between the macular microstructure of the idiopathic macular epiretinal membrane(IMEM)and ocular vision and color vision.Methods A total of 30 monocular IMEM patients(60 eyes)who were admitted to Department of Ophthalmology of Dalian Friendship Hospital from January 2019 to January 2021 were selected as the research subjects.According to whether these eyes with IMEM or not,they were divided into IMEM eye group and control group,with 30 eyes in each group.The best correlated visual acuity(BCVA)of the two groups were observed,the color vision was examined by Farnsworth Munsell 100 Hue Test(FM 100 Hue Test),and central foveal thickness(CFT)was examined by frequency domain optical coherence tomography(SD-OCT).The continuity of ellipsoid zone(EZ)in macular area was observed and analyzed statistically.Results The BCVA of IMEM eye group was lower than control group,the color vision score was higher than control group,the CFT was thicker than control group,the differences were statistically significant(P<0.05).BCVA with complete EZ continuity was higher than that with EZ continuity interruption,and the color vision score was lower than that with EZ continuity interruption,the differences were statistically significant(P<0.05).CFT and IMEM grades were positively correlated with BCVA and color vision scores(P<0.05),and age was positively correlated with color vision scores(P<0.05).Conclusion BCVA and color vision of IMEM eyes were lower than control eyes,and CFT were thicker than control eyes.The elder the age,the higher the grade of IMEM and the thicker CFT,as well as the worse BCVA and color vision.BCVA and color vision of IMEM with continuous EZ were better than those with discontinuous EZ.
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