1例疑似神经阻滞剂恶性综合征患儿不良反应分析  

Adverse Drug Reactions of Suspected Neuroleptic Malignant Syndrome in a Child

作　　者：赵一鸣[1] 史强[1] 刘小会[1] 王晓玲[1] Zhao Yiming;Shi Qiang;Liu Xiaohui;Wang Xiaoling(Beijing Children’s Hospital,Capital Medical University,Beijing 100045,China)

机构地区：[1]首都医科大学附属北京儿童医院,北京100045

出　　处：《儿科药学杂志》2021年第9期34-36,共3页Journal of Pediatric Pharmacy

摘　　要：目的:通过分析1例抽动症患儿使用氟哌啶醇导致神经阻滞剂恶性综合征的不良反应,为合理用药提供参考建议。方法:判断该神经阻滞剂恶性综合征和氟哌啶醇的相关性,并分析发生的原因和易感因素。结果:氟哌啶醇很可能是引起了该患儿神经阻滞剂恶性综合征的药物,经过药物的调整,病情已得到控制。结论:在使用氟哌啶醇时应密切监测患儿症状、体征,避免过快调整剂量,以免发生严重不良反应。Objective:To analyze the adverse drug reactions of neuroleptic malignant syndrome induced by haloperidol in a child with transient tic disorder,so as to provide reference for rational drug use.Methods:The correlation between neuroleptic malignant syndrome and haloperidol was determined,and the causes and susceptibility factors were analyzed.Results:Haloperidol was probably the drug that induced neuroleptic malignant syndrome in the child,and the condition was under control after medication modification.Conclusion:During the use of haloperidol,symptoms and signs should be closely monitored,and the dosage should be adjusted properly to avoid severe adverse drug reactions.

关 键 词：氟哌啶醇 神经阻滞剂恶性综合征 抽动症 临床药师 

分 类 号：R748[医药卫生—神经病学与精神病学]