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作 者:Zhi-Chao Chen Wei Du Ying-Chun Chen
机构地区:[1]Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University,Chengdu 610041,China [2]College of Pharmacy,Third Military Medical University,Shapingba,Chongqing 400038,China
出 处:《Chinese Journal of Chemistry》2021年第7期1775-1786,共12页中国化学(英文版)
基 金:We are grateful for the financial support from the NSFC(21931006 and 21961132004);the Fundamental Research Funds for the Central Universities,and China Postdoctoral Science Foundation(2019M663488);Postdoctoral Foundation of Sichuan University(2020SCU12019).
摘 要:Asymmetric aminocatalysis has become one of the most powerful strategies for the transformations of carbonyl substances over the past two decades.Here,we describe the research from our laboratory that significantly expands the horizon of aminocatalysis.It includes the development and application of cinchona-based primary amines,fruitful reactions based on HOMO-raising strategy,and the disclosure of amine/thiol double activation catalysis.
关 键 词:ORGANOCATALYSIS AMINOCATALYSIS Amine/thiol double catalysis CYCLOADDITION Domino reactions
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