Protecting-Group-Free Total Synthesis of(-)-Pallambins A-D  

作　　者：Xiwu Zhang Yuan Wang Peng Chen Xinxian Cai Yanxing Jia 

机构地区：[1]State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University,38 Xueyuan Road,Beijing,100191 China

出　　处：《Chinese Journal of Chemistry》2021年第7期1983-1996,共14页中国化学（英文版）

基　　金：This research was supported by the National Natural Science Foundation of China(Nos.21925101 and 21572008).

摘　　要：Main observation and conclusion A full account of the total synthesis of(-)-pallambins A-D(1-6)is described.The strategy was devised by simulating their biosynthetic pathway.The left-part bicyclo[3.2.1]octane system of pallambins C and D was efficiently constructed via a palladium-catalyzed oxidative cyclization.

关 键 词：TERPENOIDS Total synthesis ENANTIOSELECTIVITY Protecting-Group-Free Natural products 

分 类 号：O62[理学—有机化学]