有氧运动对男性酒精依赖者抑制功能的干预效果  

Intervention effect of aerobic exercise on inhibition function in male alcohol addicts

作　　者：覃颖 罗禹 赵静雯 刘燕菁 杨勇 靳泽宇 念靖晴 QIN Ying;LUO Yu;ZHAO Jingwen;LIU Yanjing;YANG Yong;JING Zeyu;NIAN Jingqing(Department of Psychiatry,the Second People's Hospital of Guizhou Province,Guiyang 550004,Guizhou,China;Department of Psychiatry,Guizhou Normal University,Guiyang 550025,Guizhou,China)

机构地区：[1]贵州省第二人民医院精神科,贵州贵阳550004 [2]贵州师范大学心理学院,贵州贵阳550025

出　　处：《贵州医科大学学报》2021年第9期1037-1041,共5页Journal of Guizhou Medical University

基　　金：贵州省卫生健康委科学技术基金(gzwjkj2019-1-114);贵州省中医药、民族医药科学技术研究专项课题(QZYY-2019-030);贵阳市科技计划项目[筑科合同(2019)2-11]。

摘　　要：目的探讨有氧运动对男性酒精依赖者抑制功能的干预效果。方法选取男性酒精依赖者50人作为研究对象,随机均分为第1组和第2组,采用交叉设计分2个阶段进行干预,第1阶段中第1组男性酒精依赖者给予有氧运动干预、第2组给予阅读干预,干预第7天时开始的第2阶段2组男性酒精依赖者干预方式进行交换;收集2组男性酒精依赖者人口学资料、饮酒信息及蒙特利尔认知评估量表(MoCa)测评结果,采用酒精相关线索的按键反应(Go)/无Go(NoGo)任务测评2组男性酒精依赖者干预前后的抑制功能。结果2组男性酒精依赖者的人口学资料、饮酒信息及MoCa测评比较,差异均无统计学意义(P>0.05);2组男性酒精依赖者在不同干预条件下、测试时间和图片类型下Go试次的平均反应时进行比较,测试时间的主效应有统计学意义(F=8.15,P<0.01,η_(p)^(2)=0.02),图片类型的主效应差异无统计学意义(F=0.006,P=0.938);对2组男性酒精依赖者在不同干预条件下、测试时间和图片类型下NoGo试次的平均错误率进行比较,测试时间主效应有统计学意义(F=4.366,P<0.05,η_(p)^(2)=0.01),在第2阶段酒精依赖者于阅读干预下的错误率(0.064±0.138)高于有氧运动干预下的错误率[(0.039±0.042);F=4.721,P<0.05,η_(p)^(2)=0.01],在第2阶段酒精依赖者于有氧运动干预下的错误率(0.037±0.038)低于阅读干预的错误率[(0.065±0.138);F=3.44,P=0.064,η_(p)^(2)=0.01]。结论有氧运动可缩短男性酒精依赖者Go试次的平均反应时,降低NoGo试次的平均错误率,从而一定程度上能改善其抑制功能。Objective To explore the intervention effect of aerobic exercise on behavioral characteristics of inhibition function in male patients with alcohol addiction.Methods Fifty male alcohol addicts were divided into Group 1 and Group 2.The intervention was conducted in two stages by cross design.In the first stage,Group 1 was given aerobic exercise intervention and Group 2 was given reading intervention.Seven days later,the intervention methods of Group 2 were exchanged in the second stage;The demographic data,drinking information and Montreal Cognitive Assessment Scale(MoCa)of two groups were collected.The Go/NoGo task of alcohol related clues was used to evaluate the inhibitory function of the subjects before and after the intervention.Results There was no significant difference in demographic data,drinking information and MoCa evaluation between the two groups(P>0.05);The average reaction time of Go trials in two groups under different intervention conditions,test time and picture types were compared.The main effect of test time was statistically significant(F=8.15,P<0.01,η_(p)^(2)=0.02);There was no significant difference in the main effect of picture type(F=0.006,P=0.938);The average error rates of NoGo trials in two groups under different intervention conditions,test time and picture types were compared.The main effect of test time was statistically significant(F=4.366,P<0.05,η_(p)^(2)=0.01);In stage 2,the error rate of male alcohol addicts under reading intervention(0.064±0.138)was higher than that under aerobic exercise intervention[(0.039±0.042);F=4.721,P<0.05,η_(p)^(2)=0.01];In stage 2,the error rate of male alcohol addicts under aerobic exercise intervention(0.037±0.038)was lower than that of reading intervention[(0.065±0.138);F=3.44,P=0.064,η_(p)^(2)=0.01].Conclusion Aerobic exercise can shorten the average reaction time of Go trials,reduce the average error rate of NoGo trials,and improve its inhibition function to a certain extent.

关 键 词：行为 成瘾 酒精依赖 有氧运动 抑制功能 复饮 Go/NoGo任务 线索诱导 

分 类 号：R749.99[医药卫生—神经病学与精神病学]