微创血肿穿刺抽吸术与小骨窗血肿清除术治疗高血压脑出血患者的效果比较  

Comparison of effects of minimally invasive hematoma puncture suction and small bone window hematoma removal in treatment of patients with hypertensive cerebral hemorrhage

作　　者：朱海 金焱 ZHU Hai;JIN Yan(Department of Neurosurgery of the Third People’s Hospital of Liaoyang,Liaoyang 111000 Liaoning,China)

机构地区：[1]辽阳市第三人民医院神经外科,辽宁辽阳111000

出　　处：《中国民康医学》2021年第16期107-109,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:比较微创血肿穿刺抽吸术与小骨窗血肿清除术治疗高血压脑出血患者的效果。方法:选取78例高血压脑出血患者为研究对象,按照随机数字表法分为对照组和观察组各39例。对照组采用小骨窗血肿清除术治疗,观察组采用微创血肿穿刺抽吸术治疗,比较两组疗效、围手术期相关指标水平、手术前后美国国立卫生研究院卒中量表(NIHSS)评分、日常生活能力量表(ADL)评分和血清炎性因子[白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)]水平。结果:观察组临床治疗总有效率为97.44%,明显高于对照组的76.92%,差异有统计学意义(P<0.05);观察组手术时间、术后下床活动时间、住院时间均短于对照组,术中失血量少于对照组,差异有统计学意义(P<0.05);手术后,两组NIHSS评分均低于手术前,且观察组低于对照组,两组ADL评分均高于手术前,且观察组高于对照组,差异有统计学意义(P<0.05);术后3 d,两组TNF-α、IL-1β水平均高于手术前,但观察组低于对照组,差异有统计学意义(P<0.05)。结论:微创血肿穿刺抽吸术治疗高血压脑出血患者可提高治疗总有效率和ADL评分,改善围手术期相关指标水平,以及降低NIHSS评分和血清炎性因子水平,优于小骨窗血肿清除术治疗效果。Objective:To compare effects of minimally invasive hematoma puncture suction and small bone window hematoma removal in treatment of patients with hypertensive cerebral hemorrhage.Methods:78 patients with hypertensive intracerebral hemorrhage were selected as the research objects,and were divided into control group and observation group according to the random number table method,39 cases in each group.The control group was treated with small bone window hematoma removal,while the observation group was treated with minimally invasive hematoma puncture suction.The efficacy,the perioperative related indicator levels,the National Institutes of Health stroke scale(NIHSS)scores before and after the surgery,the activity of daily living(ADL)score,and the serum inflammatory factors[interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)]levels were compared between the two groups.Results:The total effective rate of clinical treatment in the observation group was 97.44%,which was significantly higher than 76.92%in the control group,and the difference was statistically significant(P<0.05).The operation time,the out-of-bed time,and post-operation hospitalization time in the observation group were shorter than those in the control group;the intraoperative blood loss was less than that in the control group;and the differences were statistically significant(P<0.05).After the surgery,the NIHSS scores of the two groups were lower than those before the operation,and that of the observation group was lower than that of the control group;the ADL scores of the two groups were higher than that those before the operation,and that of the observation group was higher than that of the control group;and the differences were statistically significant(P<0.05).3 days after the surgery,the levels of TNF-αand IL-1βin the two groups were higher than those before the surgery;but those of observation group were lower than those of the control group;and the differences were statistically significant(P<0.05).Conclusions:Minimally invasive hema

关 键 词：高血压脑出血 微创血肿穿刺术 小骨窗血肿清除术 炎性因子 神经功能缺损 日常生活能力 

分 类 号：R743.34[医药卫生—神经病学与精神病学]