视神经脊髓炎谱系疾病合并免疫性血小板减少症一例  

Neuromyelitis optica spectrum disorders complicated with immune thrombocytopenia:a case report

作　　者：傅磊 沈磊[1] 卞建军[1] 李亮[1] 左金曼 葛书亚 陆尧 孟美丽[1] 苏玉璇[1] Fu Lei;Shen Lei;Bian Jianjun;Li Liang;Zuo Jinman;Ge Shuya;Lu Yao;Meng Meili;Su Yuxuan(Department of Hematology,the Second Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui 233020,China)

机构地区：[1]蚌埠医学院第二附属医院血液内科,233020

出　　处：《中华神经科杂志》2021年第9期943-945,共3页Chinese Journal of Neurology

基　　金：蚌埠医学院自然科学类基金(BYKY2019156ZD)。

摘　　要：视神经脊髓炎谱系疾病(NMOSD)是一种严重的致残性中枢神经系统自身免疫性炎性脱髓鞘病。NMOSD合并免疫性血小板减少症(ITP)临床罕见。本文报道1例既往曾多年被误诊为多发性硬化,后出现血小板明显减少,经完善检查确诊ITP,给予免疫抑制、促血小板生成治疗后血小板恢复正常的NMOSD患者的临床资料。通过对该病例资料及相关文献的复习,能提高对此类疾病的认识,及时诊治,避免发生严重并发症。Neuromyelitis optica spectrum disorders(NMOSD)are a severe autoimmune inflammatory demyelinating disease of the central nervous system.NMOSD complicated with immune thrombocytopenia(ITP)is rare.This paper reports a case of NMOSD who was misdiagnosed as multiple sclerosis for many years,and then developed thrombocytopenia.ITP was diagnosed by perfect examination.After immunosuppression and thrombopoiesis therapy,the platelets returned to normal.The review of the case and literatures can help to improve the understanding of this kind of disease,timely diagnose and treat patients,and avoid serious complications.

关 键 词：视神经脊髓炎 血小板减少 自身免疫 

分 类 号：R744.52[医药卫生—神经病学与精神病学] R558.2[医药卫生—临床医学]