新型冠状病毒肺炎疫情对武汉孕产妇抑郁和焦虑情绪的影响  

Impact of the COVID-19 outbreak on depression and anxiety among perinatal women in Wuhan

作　　者：万杏[1] 侯家保[1] 胡敏[2] WAN Xing;HOU Jiabao;HU Min(Dept.of Anesthesiology,Renmin Hospital of Wuhan University,Wuhan 430060,China;Dept.of Obstetrics,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院麻醉科,湖北武汉430060 [2]武汉大学人民医院产科,湖北武汉430060

出　　处：《武汉大学学报（医学版）》2021年第5期724-728,共5页Medical Journal of Wuhan University

基　　金：中央高校基本科研业务费专项资金(编号:2042019kf0061);武汉大学人民医院引导基金(编号:RMYD2018M03)。

摘　　要：目的:评估新型冠状病毒肺炎疫情对武汉围产期孕妇抑郁和焦虑状况的影响及因素分析。方法:选取2020年1月24日至3月29日间,在我院生产的孕妇176人,评估患者的一般资料,采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评估产前抑郁和焦虑情绪状况,采用爱丁堡产后抑郁量表(EPDS)评估产后10 d抑郁状况,并对产妇出现抑郁和焦虑的主要影响因素进行相关分析。结果:新冠肺炎疫情期间,产前焦虑情绪(SAS评分≥50)发生率为47.73%(84例),产前抑郁情绪(SDS严重度≥0.5)发生率为54.55%(96例),产后抑郁发生率为44.89%(79例)。产前SAS评分越高则产后抑郁发生率越高,两者呈中度正相关(r=0.641,P<0.001);产前SDS评分越高则抑郁症发生率越高,两者呈中度正相关(r=0.740,P<0.001)。二元Logistic回归分析显示:担心肺炎感染风险(OR=3.816,95%CI:1.688~8.627,P=0.001),睡眠质量差(OR=2.448,95%CI:1.053~5.694,P=0.038),配带口罩呼吸困难(OR=2.464,95%CI:1.009~6.014,P=0.048)是疫情流行期间产后抑郁症状的危险因素。结论:新型冠状病毒肺炎疫情增加围产期孕产妇抑郁和焦虑的发生率,其与新型冠状病毒肺炎疫情导致的多种危险因素叠加明显相关,这为预防新冠病毒肺炎疫情期间产后抑郁的发生提供有效防治策略。Objective:To evaluate the effect and analysis of coronavirus disease 2019(COVID-19)on depression and anxiety of perinatal women in Wuhan.Methods:A total of 176 perinatal women were selected,who were delivered in Renmin Hospital of Wuhan University from January 24 to March 29,2020.The general information of the patients was evaluated.The anxiety self-assessment scale(SAS)and depression self-assessment(SDS)were used before delivery.The Edinburgh Postpartum Depression Scale(EPDS)was used to assess depression from 10 days to 14 days after delivery.The main factors affecting maternal depression and anxiety were investigated and analyzed.Results:During the outbreak of COVID-19,the incidence of anxiety(SAS score≥50)was 47.73%(84 cases),and the incidence of depression(SDS score≥0.5)was 54.55%(96 cases)before delivery.The incidence of depression(EPDS score≥0.5)was 44.89%(79 cases)after delivery.The prenatal SAS score was related to depression after delivery(r=0.641,P<0.001),and the prenatal SDS score was also related to depression after delivery(r=0.740,P<0.001).Logistic analysis indicated that worrying about the risk of COVID-19 infection(OR=3.816,95%CI:1.688-8.627,P=0.001),poor sleep quality(OR=2.448,95%CI:1.053~5.694,P=0.038)and dyspnea in mask(OR=2.464,95%CI:1.009-6.014,P=0.048)were the main risk factors for postpartum depression in pregnant women during outbreak of COVID-19.Conclusion:The outbreak of COVID-19 increased the incidence of maternal depression and anxiety during perinatal period,which was significantly related to the combination of multiple risk factors caused by the outbreak of COVID-19.These provide an effective prevention strategy for preventing the postpartum depression during the outbreak of COVID-19.

关 键 词：新型冠状病毒肺炎 产后抑郁 焦虑 孕产妇 

分 类 号：R749[医药卫生—神经病学与精神病学]