卵圆孔未闭相关性卒中的诊治研究进展  

Progress in Diagnosis and Treatment of Stroke Related with Patent Foramen Ovale

作　　者：王泽祎 杨亭亭 刘广志 WANG Ze-Yi;YANG Ting-Ting;LIU Guang-Zhi(Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China)

机构地区：[1]首都医科大学附属北京安贞医院,北京100029

出　　处：《中国卒中杂志》2021年第9期960-966,共7页Chinese Journal of Stroke

摘　　要：卵圆孔未闭(patent foramen ovale,PFO)与卒中发病有明显的关联。应利用卒中高风险PFO解剖学特征、卒中影像特征及反常栓塞风险量表等,经多科综合评估,选择患者最适合的治疗方案。多数现有研究及指南支持对于卒中高风险PFO患者,首选PFO封堵术加术后长期抗血小板治疗;单独抗凝治疗与单独抗血小板治疗在预防卒中复发上同效。Patent foramen ovale(PFO)is strongly associated with cryptogenic stroke.For the patients with high-risk PFO,the appropriate treatment is decided by comprehensive evaluation including the high-risk PFO anatomical features,stroke imaging features and risk of paradoxical embolism(RoPE)scale,etc.Most of the existing research and guidelines support that PFO closer plus long-term antiplatelet therapy should be preferred for the patients with high-risk PFO,but the postoperative complications such as atrial fibrillation and occluder-related thrombosis may occur.Anticoagulation therapy and antiplatelet therapy are equally effective in preventing recurrent stroke.

关 键 词：卵圆孔未闭 隐源性卒中 心源性卒中 封堵术 

分 类 号：R743.3[医药卫生—神经病学与精神病学]