Nestin与乳腺癌发生发展关系  

Relationship between nestin and occurrence and development of breast cancer

作　　者：郭亚瑞 周伟强 GUO Yarui;ZHOU Weiqiang(Postgraduate of Grade 2020,Shenyang Medical College,Shenyang 110034,China;Department of Pathogen Biology,Shenyang Medical College,Shenyang 110034,China)

机构地区：[1]沈阳医学院基础医学院,辽宁沈阳110034 [2]沈阳医学院基础医学院病原生物学教研室,辽宁沈阳110034

出　　处：《沈阳医学院学报》2021年第5期417-420,共4页Journal of Shenyang Medical College

基　　金：国家自然科学基金资助项目(No.81172509);辽宁省教育厅科技项目(No.SYYX202004);沈阳市科技局科技项目(No.20-205-4-066);沈阳医学院研究生创新基金(No.Y20210501)。

摘　　要：乳腺癌是目前女性最常见的恶性肿瘤,由于其高患病率以及高死亡率,严重威胁女性的健康和生活。有研究表明Nestin在多种癌症中与新血管生成密切相关,在乳腺癌患者中,也能检测到Nestin的表达增高,并且其与乳腺癌转移、进展和预后等相关。本文将对Nestin以及其对癌症尤其是乳腺癌发生发展的关系作一简要综述。Breast cancer is currently the most common malignant tumor in women,which poses a serious threat to women′s health and life due to its high prevalence and mortality.Studies have shown that nestin is closely related to neoangiogenesis in a variety of cancers.In breast cancer patients,the increased expression of nestin can also be detected and is related to metastasis,progression and prognosis of breast cancer.This article reviews nestin and its relationship to the development and progression of cancer,particularly breast cancer.

关 键 词：NESTIN 乳腺癌 肿瘤标记物 血管生成 

分 类 号：R737.9[医药卫生—肿瘤]