神经调控治疗癫痫的基础研究现状与展望  

The present status and prospect of basic research on neuromodulation therapy for epilepsy

作　　者：刘冲[1,2] 孟凡刚 Liu Chong;Meng Fangang(Beijing Neurosurgical Institute,Capital Medical University,Beijing 100070,China;Beijing Key Laboratory of Neurostimulation,Beijing 100070,China;Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Chinese Institute for Brain Research,Beijing 102206,China)

机构地区：[1]首都医科大学,北京市神经外科研究所,100070 [2]神经电刺激研究与治疗北京市重点实验室,100070 [3]首都医科大学附属北京天坛医院,100070 [4]北京脑科学与类脑研究中心,102206

出　　处：《中华实验外科杂志》2021年第9期1633-1637,共5页Chinese Journal of Experimental Surgery

基　　金：国家自然科学基金(81971070);北京市医院管理局临床医学发展专项(XMLX201833)。

摘　　要：癫痫是神经系统常见的疾病类型,具有发作性、反复性的特点,是临床难以攻克的难题之一。对于不适合手术治疗、药物控制不佳的难治性癫痫,神经调控技术是一种有效治疗手段,其中以神经电刺激应用最早、也最为广泛。本文结合最新的神经调控基础研究,旨在更加充分地了解神经调控技术的治疗机制和未来发展方向。Epilepsy is a common disease type of the nervous system.It is characterized by episodic and repetitive attacks and is one of the difficult clinical problems to overcome.For intractable epilepsy that is not suitable for surgical treatment and poor drug control,neuromodulation technology is an effective treatment method,among which neuroelectric stimulation is the earliest and most widely used.This article combines the latest basic research on neuromodulation to fully understand the therapeutic mechanism and future development direction of neuromodulation technology.

关 键 词：癫痫 神经调控 

分 类 号：R742.1[医药卫生—神经病学与精神病学]