肿瘤PET乏氧显像的临床研究进展  

Clinical research progress of PET imaging in tumor hypoxia

作　　者：马苑 付秀华[2] 王立红[2] 顾岩[2] Ma Yuan;Fu Xiuhua;Wang Lihong;Gu Yan(Department of Cadre Health Care,Inner Mongolia People′s Hospital,Hohhot 010017,China;Department of Respiratory and Critical Care Medicine,Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050,China)

机构地区：[1]内蒙古自治区人民医院干部保健所,呼和浩特010017 [2]内蒙古医科大学附属医院呼吸与危重症医学科,呼和浩特010050

出　　处：《中华核医学与分子影像杂志》2021年第9期562-565,共4页Chinese Journal of Nuclear Medicine and Molecular Imaging

基　　金：内蒙古自治区自然科学基金(2018LH08026)。

摘　　要：乏氧是实体瘤的常见现象,与肿瘤的增殖、恶性进展、放化疗抵抗、耐药性、治疗失败、不良预后密切相关。目前较多的相关研究集中于应用影像学、核医学方法检测肿瘤乏氧区域方面。该文对肿瘤乏氧微环境的检测及多种PET显像剂应用于肿瘤乏氧显像的研究进展进行综述。Hypoxia is a common phenomenon of solid tumor,which is closely related to the malignant proliferation,tumor progression,radiotherapy and chemotherapy resistance,treatment failure,and poor prognosis.At present,many researches focus on the application of medical imaging and nuclear medicine methods in detecting the hypoxic areas of tumors.This article focuses on the detection of hypoxia microenvironment and the application of PET tracers in tumor hypoxia imaging.

关 键 词：肿瘤 缺氧 正电子发射断层显像术 发展趋势 

分 类 号：R730.44[医药卫生—肿瘤]