复明片联合卵磷脂络合碘片治疗玻璃体混浊的临床疗效  

Clinical effect of Fuming tablets combined with lecithin complexed iodine tablets in the treatment of vitreous opacities

作　　者：孙宁 徐东强 SUN Ning;XU Dongqiang(General Hospital of Central Theater Command of the PLA,Wuhan 475003,China)

机构地区：[1]中国人民解放军中部战区总医院眼科,湖北武汉475003

出　　处：《药学实践杂志》2021年第5期476-478,共3页Journal of Pharmaceutical Practice

摘　　要：目的分析复明片与卵磷脂络合碘片联合治疗玻璃体混浊的临床疗效。方法前瞻性研究,选取中部地区总医院2019年5月至2020年5月眼科收治的80例玻璃体混浊患者为研究对象,按照随机分组法,将患者划分为对照组和观察组,对照组患者口服卵磷脂络合碘片进行治疗,观察组患者口服复明片联合卵磷脂络合碘片治疗,比较两组治疗前后视力及玻璃体混浊程度变化情况,对比两组疗效。结果治疗后两组患者视力水平均有提高,观察组的视力水平明显高于对照组,差异有统计学意义(P<0.05);玻璃体混浊程度评分治疗前两组无差异,治疗后观察组改善幅度更大,与对照组相比差异有统计学意义(P<0.05);观察组治疗有效率为95.0%(38/40),明显高于对照组的80.0%(32/40),差异有统计学意义(P<0.05);两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论复明片与卵磷脂络合碘片联用治疗玻璃体混浊,在改善患者视力及玻璃体混浊程度方面作用突出,具有较好的有效性和安全性,值得在临床治疗上推广应用。Objective To analyze the clinical efficacy of Fuming tablets and lecithin-complexed iodine tablets in the treatment of vitreous opacities.Methods 80 patients with vitreous opacities admitted to the department of ophthalmology in the central region general hospital from May 2019 to May 2020 were selected for this research.According to the random grouping method,the patients were divided into a control group and an observation group.The control group patients received lecithin-complexed iodine tablets orally for the treatment.The observation group was treated with Fuming tablets combined with lecithin-complexed iodine tablets.The therapeutic effects in the two groups were evaluated by comparing the visual acuity and vitreous opacity of the two groups before and after treatment.Results The visual acuity level was improved in both groups after the treatments.The visual acuity level in the observation group was significantly higher than that in the control group with statistical significance(P<0.05).There was no difference in the degree of vitreous opacity score between the two groups before treatment.The vitreous opacity score improvement in the observation group was greater than that in control group after the treatment with statistical significance(P<0.05).The treatment effective rate in the observation group was 95.0%(38/40),which was significantly higher than the control group,80.0%(32/40).The difference was statistically significant(P<0.05).There was no statistically significant difference in adverse reactions between the two groups(P>0.05).Conclusion Fuming tablets combined with lecithin-complexed iodine tablets have outstanding therapeutic effects in improving the vision and degree of vitreous opacities.This combination therapy deserves the extensive clinical applications.

关 键 词：复明片 卵磷脂络合碘片 玻璃体混浊 视力 不良反应 临床疗效 

分 类 号：R776.4[医药卫生—眼科]