中药藤茶化学成分及抗感染作用研究进展  

Research Progress on Chemical Constituents and Anti-infective Effects of the Traditional Chinese Medicine Vine Tea(Ampelopsis grossedentata)

作　　者：张云坤 李娟 黄丹 欧阳文 姚蓉 何寿生 李顺祥 Zhang Yunkun;Li Juan;Huang Dan;Ouyang Wen;Yao Rong;He Shousheng;Li Shunxiang(Hunan Province Engineering Research Center of Bioactive Substance Discovery of TCM,School of Pharmacy,Hunan University of Chinese Medicine,Changsha 410208,China;Hunan Food and Drug Vocational College,Changsha 410208,China;Hunan Medical Products Administration,Changsha 410013,China)

机构地区：[1]湖南中医药大学药学院/湖南省中药活性物质筛选工程技术研究中心,长沙410208 [2]湖南食品药品职业学院,长沙410208 [3]湖南省药品监督管理局,长沙410013

出　　处：《世界科学技术-中医药现代化》2021年第6期2012-2022,共11页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：湖南省科学技术厅2020年度创新型省份建设专项抗击新冠肺炎疫情专题项目(2020SK3035):新型冠状病毒快速检测、病毒阻断治疗研究与应用,负责人:李顺祥;湖南省食品药品监督管理局食品药品安全科技项目(湘食药科R201806):湖南特色药材质量标准提升研究,负责人:张云坤;湖南中医药大学中药学一流学科项目(校行科字【2018】3号):藤茶的物质基础与应用,负责人:李顺祥。

摘　　要：藤茶是一种在中国南方地区广泛应用的保健茶和中草药,在民间已有上千年的应用历史,常用于治疗口腔溃疡、咽喉肿痛、感冒发热、湿热黄疸、目赤肿痛、痈肿疮疖等症。本文通过检索中国知网、PubMed、Scifinder等数据库,系统调研相关文献资料,对中药藤茶的化学成分、抗感染作用研究现状进行综述,以期为藤茶的进一步研究和开发提供参考。藤茶中主要含黄酮类、甾体类、萜类、多酚、多糖类等化学成分,具有显著的抗病毒、抗菌、抗炎、调节免疫等抗感染生物活性,可通过直接或间接作用等多种途径达到抑制病原微生物及其引起的病变,具有广阔的开发应用前景。Vine tea(Ampelopsis grossedentata(Hand-Mazz)W.T.Wang),a widely used healthy tea and herbal medicine in Southern China,has been widely used in the treatment of oral ulcer,sore throat,cold fever,damp heat jaundice,red eye swelling and pain,carbuncle,swelling and furuncle.To provide references for the further studies and development of the traditional Chinese medicine Vine Tea(Ampelopsis grossedentata),a systematic literature survey was conducted to summarize the chemical constituents and its anti-infective effects of Vine Tea by retrieving CNKI、PubMed and Scifinder databases.Vine Tea mainly contains flavonoids,steroids,terpenoids,polyphenols,polysaccharides and other chemical components.It has significant anti-infective biological activities such as antiviral,antibacterial,antiinflammatory,and immune regulation.It can inhibit pathogenic microorganism and its pathological changes through direct or indirect actions,which has broad prospects for development and applications.

关 键 词：藤茶 化学成分 抗感染作用 研究进展 

分 类 号：R284.1[医药卫生—中药学]