口腔挥发性硫化物的产生与针对性防治的研究进展  

Volatile sulfur compounds and its role in the management of intra-oral halitosis

作　　者：黄培勍 彭显 徐欣[1] Huang Peiqing;Peng Xian;Xu Xin(State Key Laboratory of Oral Disease&National Clinical Research Center for Oral Diseases&Dept.of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)

机构地区：[1]口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心,四川大学华西口腔医院牙体牙髓病科,成都610041

出　　处：《国际口腔医学杂志》2021年第5期592-599,共8页International Journal of Stomatology

基　　金：国家自然科学基金面上项目(81771099)。

摘　　要：口源性口臭是一种常见的口腔临床病症,与口腔内厌氧菌分解代谢蛋白质,产生挥发性硫化物(VSCs)密切相关。口腔中VSCs的产生与舌苔增厚及牙周炎发生有着重要联系,针对性抑制VSCs产生也是当前减轻口源性口臭症状的研究热点。本文对近年来关于口腔中VSCs的来源以及通过控制细菌及菌斑、直接作用于VSCs等手段治疗口源性口臭的进展进行综述,以期对VSCs的产生及因其导致的口源性口臭的防治提供依据和思路。Intra-oral halitosis is one of the most frequent complaints of patients seeking oral treatment, which is mainly produced due to the breakdown of certain amino acids by anaerobic bacterium, followed by the release of volatile sulfur compounds(VSCs). It is generally considered that VSCs are closely related with tongue coating and periodontitis.This review summarizes the source of VSCs and the progress on the treatments of intra-oral halitosis, which are aimed at controlling dental plaque or reacting directly with VSCs. Research advancement in this field provides not only evidence for halitosis therapy, but new ideas and methods of halitosis treatment.

关 键 词：口源性口臭 挥发性硫化物 口腔厌氧菌 牙菌斑生物膜 

分 类 号：R781[医药卫生—口腔医学]