不同药液温度下复方聚乙二醇电解质散的病人耐受性及结肠清洁效果分析  

Patient tolerance and colon cleansing effect of polyethylene glycol electrolytes powder under different liquid temperatures

作　　者：李妙芳 蔡剑梅[1] LI Miaofang;CAI Jianmei(Department of Gastroenterology,The Second Affiliated Hospital of Guangxi Medical University,Nanning,Guangxi Zhuang Autonomous Region 530007,China)

机构地区：[1]广西医科大学第二附属医院消化内科,广西壮族自治区南宁530007

出　　处：《安徽医药》2021年第10期2110-2112,共3页Anhui Medical and Pharmaceutical Journal

基　　金：广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z2016733)。

摘　　要：目的探讨不同复方聚乙二醇电解质散(和爽)药液温度对病人耐受性及结肠清洁效果的影响,筛选出最佳药液温度供临床使用。方法选择2017年1月至2019年11月广西医科大学第二附属医院收治的180例住院需做肠镜检查及治疗的病人为研究对象。按照随机数字表法分为A组(服用25-30℃药液)、B组(服用30-35℃药液)和C组(服用35-38℃药液),每组各60例。清肠药物采用和爽,使用医院内自制饮用纯净水作为溶媒配置成2 L溶液,口服,1 h内服完。所有病人均在16-18点进行镜检并进行清肠效果评估。比较三组病人的排便时间、耐受性及结肠清洁效果。结果三组病人排便时间及药物耐受性差别无统计学意义,且可耐受病人比例均在88.0%以上。在结肠清洁效果比较上,A、B、C组清洁效果达到优良的分别为33、42、59例。A组和B组清洁效果在优良以上的病例比例在70.0%以下,C组在98.0%以上。结论采用35-38℃药液进行清肠可以获得最佳清肠效果,可以在临床推广使用。Objective To explore the effect of different temperatures of polyethylene glycol electrolytes powder(Ⅱ)solution on patients’tolerance and colon cleansing effect,and to select the best temperature for clinical use.Methods A hundred and eighty patients,who were hospitalized in The Second Affiliated Hospital of Guangxi Medical University from January 2017 to November 2019 and were in need of colonoscopy and treatment,were selected as the study subjects.According to the random number table method,they were assigned into group A(taking drug liquid at 25-30℃),group B(taking drug liquid at 30-35℃)and group C(taking drug liquid at 35-38℃),60 cases in each group.Polyethylene glycol electrolytes powder(Ⅱ)was used as the bowel cleansing drug,and the pure drinking water made in the hospital was used as the solvent to prepare 2 L solution,which was taken orally within 1 hour.All patients were examined under colonscope from 16 to 18 p.m.and the effect of bowel cleansing was evaluated.Finally we compared the defecation time,tolerance and colon cleansing effect among the three groups.Results There were no significant differences in defecation time and drug tolerance among the three groups,and the proportions of tolerable patients in the three groups were all above 88.0%.In respect of colon cleansing effect,33,42 and 59 cases in group A,B and C achieved excellent cleansing effect respectively.The proportion of cases with excellent cleansing effect in group A and group B was less than 70.0%,and that in group C was more than 98.0%.Conclusion The best colon cleansing effect can be obtained by using drug liquid at 35-38℃,which can be widely used in clinic.

关 键 词：灌肠 药液温度 复方聚乙二醇电解质散(和爽) 结肠清洁效果 

分 类 号：R735.34[医药卫生—肿瘤]