低密度脂蛋白胆固醇与糖尿病合并脑梗死或心肌梗死的相关性分析  

Correlation between low-density lipoprotein cholesterol and diabetes mellitus complicated with cerebral infarction or myocardial infarction

作　　者：石萌 SHI Meng(Community Health Service Center of Haidian District,Beijing 100096,China)

机构地区：[1]北京市海淀区海淀镇社区卫生服务中心,100096

出　　处：《中国实用医药》2021年第27期30-32,共3页China Practical Medicine

摘　　要：目的探讨低密度脂蛋白胆固醇(LDL-C)与糖尿病(DM)合并脑梗死(CI)或心肌梗死(MI)的相关性。方法240例DM患者,其中合并CI患者68例作为CI组,合并MI患者72例作为MI组,未合并CI、MI患者100例作为CG组,检测三组血脂水平,分析LDL-C与DM患者CI、MI发病的相关性。结果CI组LDL-C、总胆固醇(TC)、甘油三酯(TG)水平高于CG组,高密度脂蛋白胆固醇(HDL-C)水平低于CG组,差异有统计学意义(P<0.05);MI组LDL-C、TC水平高于CG组,差异有统计学意义(P<0.05),TG、HDL-C水平与CG组比较差异无统计学意义(P>0.05)。DM患者LDL-C与CI及MI发病均呈正相关(r=0.825、0.786,P<0.05)。结论DM合并CI患者血浆中高水平LDL-C、TC、TG和低水平的HDL-C是CI的危险因素,DM合并MI患者高水平LDL-C、TC是MI的危险因素。DM患者LDL-C与CI及MI发病均呈正相关。Objective To discuss the correlation between low-density lipoprotein cholesterol(LDL-C)and diabetes mellitus(DM)complicated with cerebral infarction(CI)or myocardial infarction(MI).Methods 240 patients with DM,of which 68 patients complicated with CI were regarded as the CI group,72 patients complicated with MI were regarded as the MI group,and 100 patients without CI or MI were regarded as the CG group.The blood lipid levels of the three groups were detected,and the correlation between LDL-C and the onset of CI and MI in DM patients was analyzed.Results The levels of LDL-C,total cholesterol(TC),and triglycerides(TG)in the CI group were higher than those in the CG group,and the high-density lipoprotein cholesterol(HDL-C)levels were lower than those in the CG group.All the difference was statistically significant(P<0.05).The levels of LDL-C and TC in the MI group were higher than those in the CG group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the levels of TG and HDL-C between CG group and MI group(P>0.05).There was a positive correlation between LDL-C and MI in patients with DM(r=0.825,0.786;P<0.05).Conclusion High levels of LDL-C,TC,TG and low levels of HDL-C in plasma are risk factors for CI in patients with DM complicated with CI,and high levels of LDL-C and TC were risk factors for MI in patients with DM combined with MI.There is a positive correlation between LDL-C and MI in patients with DM.

关 键 词：低密度脂蛋白胆固醇 糖尿病 脑梗死 心肌梗死 相关性 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R587.1[医药卫生—临床医学] R542.22