小于胎龄儿的研究进展  

Research progress in small for gestational age

作　　者：游晶玉 苏喆[1] 潘丽丽[1] YOU Jing-yu;SU Zhe;PAN Li-li(Department of Endocrinology,Shenzhen Children’s Hospital,Shenzhen 518038,China)

机构地区：[1]深圳市儿童医院内分泌科,广东深圳518038

出　　处：《中国实用儿科杂志》2021年第8期602-607,共6页Chinese Journal of Practical Pediatrics

基　　金：广东省卫生健康委员会高水平临床重点专科(深圳市配套建设经费)项目(SZGSP012);深圳市基础研究资助项目(KCXFZ20201221173400002)。

摘　　要：我国小于胎龄儿(SGA)发生率并不低。发病机制复杂,包括胎盘、孕母和胎儿因素,其中胎儿因素越来越受到重视,尤其遗传学方面的进展。生后管理涉及追赶性生长和生长以外多系统近远期并发症的防治,前者需注意适度追赶和生长激素应用的禁忌证,后者涉及神经发育和认知、心血管和代谢并发症、青春期发育和生殖健康等。宫内和宫外生长迟缓(IUGR/EUGR)因有相似的风险,需受到临床医生同样的重视。The incidence of small for gestational age(SGA)is not low in China.The pathogenesis is complex,including placental,maternal and fetal factors.The fetal factors are getting more and more attention,especially genetic etiologies.Managements of SGA include catch-up growth and prevention and treatment of short-and long-term complications of multiple systems.Appropriate catch-up growth is important.The contraindications of growth hormones should be kept in the mind of clinical doctors.Complications of multiple systems include neural development and cognition impairments,cardiovascular and metabolic disorders,pubertal development and fertility issues.Because of similar growth risks,intrauterine and extrauterine growth retardation(IUGR/EUGR)deserves equal attention of clinical doctors.

关 键 词：小于胎龄儿 病因学 追赶性生长 认知发育 代谢性疾病 

分 类 号：R72[医药卫生—儿科]