前列腺癌图像引导放疗中骨骼对锥形束CT校准的影响研究  

Effect of skeleton on cone beam CT calibration for prostate cancer image guide radiation therapy

作　　者：田龙[1] 席强[1] 刘月霞[2] 张遵浩 TIAN Long;XI Qiang;LIU Yuexia;ZHANG Zunhao(Department of Radiotherapy,the First Affiliated Hospital of Hebei North University,Zhangjiakou 075000,Hebei,China;Department of Medical Imaging,Zhangjiakou Institute of Education,Zhangjiakou 075000,Hebei,China;Department of Radiotherapy,the First Hospital of Hebei Medical University,Shijiazhuang 050000,Hebei,China)

机构地区：[1]河北北方学院附属第一医院放疗科,河北张家口075000 [2]张家口教育学院医学影像系,河北张家口075000 [3]河北医科大学第一医院放疗科,石家庄050000

出　　处：《癌症进展》2021年第16期1655-1657,共3页Oncology Progress

摘　　要：目的利用前列腺癌患者治疗前锥形束CT(CBCT)获取的内植标记物位移信息,量化盆腔区域骨骼对图像引导放疗(IGRT)造成的影响。方法对10例内植标记物前列腺癌患者进行治疗前CBCT扫描,记录标记物于左右(LR)、头脚(SI)、前后(AP)3个方向上的位移,利用算法量化盆腔区域骨骼对CBCT校准的影响。结果标记物于LR、SI、AP 3个方向上的位移平均值分别为0.51、1.33、1.36 mm;10例患者骨骼对校准影响量化指标误差均方根(RMS)于LR、SI、AP 3个方向上的平均值分别为0.02、0.06、0.07 mm。结论盆腔区域骨骼对前列腺癌IGRT治疗中CBCT校准影响甚微,但仍需提高软硬件和图像处理水平。Objective To quantify the effect of skeleton in pelvic on image guide radiation therapy(IGRT)by using the information of displacement of implanted markers from cone beam CT(CBCT)scans for prostate cancer patients before treatment.Method Ten prostate cancer patients implanted with markers received CBCT scan before treatment and the data of displacement of markers in left-right(LR),superior-inferior(SI),and anterior-posterior(AP)direction were recorded.The effect of the skeleton in pelvic on the CBCT calibration was quantified by using the algorithm.Result The average displacement of the markers in three directions(LR,SI and AP)were 0.51,1.33,1.36 mm,respectively;and the quantitative index root mean square(RMS)of skeletal impact on calibration in three directions(LR,SI and AP)were 0.02,0.06,0.07 mm for 10 patients,respectively.Conclusion The skeleton in pelvic has little effect on CBCT calibration in IGRT of prostate cancer,but software and hardware and image processing level still need to be improved.

关 键 词：前列腺癌 锥形束CT 标记物 骨骼 误差均方根 

分 类 号：R737.25[医药卫生—肿瘤]