容积旋转调强放疗(VMRT)应用于脑胶质瘤患者的疗效  

The effect of volume rotation intensity-modulated radiotherapy(VMRT)in patients with glioma

作　　者：黄俊萍 周志宇[1] 谢昌纪[1] 蓝欢[1] 李光[1] Huang Junping;Zhou Zhiyu;Xie Changji;Lan Huan;Li Guang(Dept.of Neurosurgery,Guangxi Zhuang Autonomous Region,Nanning 530001,China)

机构地区：[1]广西壮族自治区民族医院神经外科,广西南宁530001

出　　处：《山东第一医科大学（山东省医学科学院）学报》2021年第8期598-601,共4页Journal of Shandong First Medical University ＆ Shandong Academy of Medical Sciences

基　　金：广西崇左市科学技术局(崇科FA2020024)。

摘　　要：目的对比分析容积旋转调强放疗(VMRT)、常规静态调强放疗(IMRT)治疗对脑胶质瘤的治疗效果,为临床诊疗提供参考。方法选取2018年2月—2019年4月在广西壮族自治区民族医院治疗的94例脑胶质瘤患者,将其分为两组。观察组47例,对照组47例;观察组应用VMRT治疗,对照组应用IMRT治疗。对比两组患者的HI、CI、临床疗效及生存率。结果观察组患者的CI高于对照组(P<0.05),两组患者的HI差异无统计学意义(P>0.05);观察组患者客观缓解率为80.85%,对照组为61.70%,差异具有统计学意义(P<0.05);观察组患者的半年、1年、2年生存率分别为80.85%、72.34%、53.19%,对照组患者分别为59.57%、42.55%、29.79%,差异具有统计学意义(P<0.05)。结论对脑胶质瘤患者应用VMRT治疗的CI优于IMRT,患者客观缓解率更高,且2年内生存率更高,值得推广。Objective:To analyze their therapeutic effects ofVMRT and IMRT on patients with glioma.Method:Ninety-four patients with glioma treated in our hospital from February 2018 to April 2019 were selectedand divided them into two groups.There were 47 cases in the control group and 47 cases in the control group;the 47 cases in the observation group were treated with VMRT.The HI,CI,clinical efficacy and survival rate of the two groups of patients were compared.Results:The CI of the observation group was higher than that of the control group(P<0.05),and there was no significant difference in HI between the two groups(P>0.05);the objective remission rate of the observation group was 80.85%,and the control group was 61.70%.The difference was significant(P<0.05);the half-year,one-year,and two-year survival rates of the observation group were 80.85%,72.34%,and 53.19%,respectively,and the control group were 59.57%,42.55%,and 29.79%,respectively,with significant differences(P<0.05).Conclusion:The CI of VMRT is better than IMRT for patients with glioma.The objective response rate is higher and the survival rate within 2 years is higher,which is worthy of promotion.

关 键 词：脑胶质瘤 容积旋转调强放疗 疗效 

分 类 号：R739.41[医药卫生—肿瘤]