30例消化道肿瘤骨转移患者的定量SPECT/CT显像分析  

Quantitative SPECT/CT imaging analysis of 30 cases of gastrointestinal tumors with bone metastases

作　　者：代迪 郝吉庆[1] DAI Di;HAO Jiqing(Department of Oncology,the First Affiliated Hospital of Anhui Medical University,Anhui Hefei 230022,China)

机构地区：[1]安徽医科大学第一附属医院肿瘤内科,安徽合肥230022

出　　处：《现代肿瘤医学》2021年第19期3415-3419,共5页Journal of Modern Oncology

基　　金：北京医卫健康公益基金会(编号:F3034D)。

摘　　要：目的:总结30例消化道肿瘤骨转移患者的临床资料及放射性骨显像的特点,并探讨定量SPECT/CT监测的SUV_(max)的影响因素。方法:回顾性分析2017年01月至2020年10月之间30例曾经来我院接受定量SPECT/CT检查的消化道肿瘤骨转移患者的临床资料,对消化道肿瘤骨转移的临床特点进行归纳总结,并分析定量SPECT/CT检查结果的SUV_(max)值与性别、吸烟、饮酒、骨外转移、骨转移灶数量及是否曾经使用双磷酸盐等临床数据的相关性,分析骨转移灶的数目对血钙、血磷、癌胚抗原及碱性磷酸酶等临床指标的影响。结果:患者的性别、是否吸烟饮酒、是否合并其他脏器转移及是否曾经使用双膦酸盐治疗与SUV_(max)没有明显关系,而骨转移灶数目会影响SUV_(max)的数值大小,并且骨多发转移患者的血钙水平低于单骨转移患者。结论:骨转移灶的数目是定量SPECT/CT SUV_(max)的一个影响因素,骨多发转移患者的SUV_(max)数值高于骨单发转移患者,并且消化道肿瘤骨多发转移患者的血清钙水平低于骨单发转移患者,定量SPECT/CT检查联合血清钙水平测定对消化道肿瘤骨转移具有一定的临床应用价值。Objective:To analyze and summarize the clinical data and the characteristics of radioactive bone imaging of 30 gastrointestinal tumor patients with bone metastases,and to explore the influencing factors of SUV_(max) monitored by quantitative SPECT/CT.Methods:Retrospectively analyze the clinical data of 30 gastrointestinal tumor patients with bone metastases who came to our hospital for routine SPECT/CT examination from January 2017 to October 2020.We summarized the clinical characteristics of gastrointestinal tumor with bone metastasis,and analyzed the correlation between the quantitative SPECT/CT SUV_(max) value and gender,smoking,drinking,extra-skeletal metastasis,the number of bone metastases,and whether bisphosphonates have been used before,and analyzed the effect of the number of bone metastases on blood calcium,blood phosphorus,alkali and carcinoembryonic antigen.In order to fully understand and use the results of quantitative SPECT/CT and improve the clinical application value of quantitative SPECT/CT.Results:Gender,smoking,drinking,other organ metastases,bisphosphonate therapy had no significant relationship with SUV_(max).The number of bone metastases was an influencing factor of SUV_(max),and the blood calcium level of patients with multiple bone metastases was lower than that of patients with single bone metastases.Conclusion:The number of bone metastases is an influencing factor of quantitative SPECT/CT SUV_(max).The SUV_(max) of patients with multiple bone metastasis is higher than that of patients with single bone metastasis,and the blood calcium level of patients with multiple bone metastasis is lower than that of patients with single bone metastasis.SPECT/CT examination combined with blood calcium have certain clinical diagnostic value for gastrointestinal tumor with bone metastasis.

关 键 词：定量SPECT/CT 消化道肿瘤 骨转移 

分 类 号：R735[医药卫生—肿瘤]