正中神经电刺激联合计算机辅助认知训练治疗脑卒中后认知功能障碍的效果  

Effect of median nerve electrical stimulation combined with computer-assisted cognitive training in the treatment of post-stroke cognitive dysfunction

作　　者：张霄琼 张娟 张丝丝 赵秦[1] ZHANG Xiaoqiong;ZHANG Juan;ZHANG Sisi;ZHAO Qin(Department of Rehabilitation Medicine,the First People’s Hospital of Lianyungang City,Jiangsu Province,Lianyungang222000,China)

机构地区：[1]江苏省连云港市第一人民医院康复医学科,江苏连云港222000

出　　处：《中国医药导报》2021年第26期73-76,共4页China Medical Herald

基　　金：江苏省自然科学基金资助项目(BK20151419)。

摘　　要：目的探讨正中神经电刺激联合计算机辅助认知训练治疗脑卒中后认知功能障碍的效果。方法选择2017年6月至2020年5月江苏省连云港市第一人民医院收治的94例脑卒中后认知功能障碍患者为研究对象,按照随机数字表法将其分为对照组(47例)和观察组(47例)。对照组采用计算机认知功能训练治疗,观察组在对照组的基础上采用正中神经电刺激治疗,两组治疗时间均为6周。观察两组治疗前后认知功能情况,比较两组临床疗效,比较观察组正中神经电刺激前后脑区氧合血红蛋白浓度变化。结果治疗后,两组蒙特利尔认知评估(MoCA)量表评分高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。两组临床疗效比较差异有统计学意义(P<0.05)。观察组电刺激前后左运动区、右运动区氧合血红蛋白浓度比较,差异无统计学意义(P>0.05)。观察组电刺激后左前额、右前额氧合血红蛋白浓度高于电刺激前,差异有统计学意义(P<0.05)。结论采用正中神经电刺激联合计算机辅助认知训练治疗脑卒中后认知功能障碍患者,效果显著,可改善患者的认知功能,且电刺激可提高患者双前额脑区氧合血红蛋白浓度。Objective To explore the effect of median nerve electrical stimulation combined with computer-assisted cognitive training in the treatment of post-stroke cognitive dysfunction.Methods A total of 94 patients with post-stroke cognitive dysfunction admitted to the First People’s Hospital of Lianyungang City,Jiangsu Province from June 2017 to May 2020 were selected as the study subjects.They were divided into control group(47 cases)and observation group(47 cases)according to random number table method.The control group was treated with computer-assisted cognitive training,and the observation group was treated with median nerve electrical stimulation based on the control group.The treatment time of both groups was six weeks.The cognitive function of the two groups was observed before and after treatment,the clinical efficacy of the two groups was compared,and the changes of oxygenated hemoglobin concentration in the brain area before and after median nerve electrical stimulation were compared in the observation group.Results After treatment,the scores of Montreal cognitive assessment(MoCA)scale in two groups were higher than those before treatment,and the observation group was higher than the control group,with statistical significance(P<0.05).There was statistically significant difference between the two groups(P<0.05).There was no significant difference in the oxygenated hemoglobin concentration of left motor area and right motor area in the observation group before and after electrical stimulation(P>0.05).The oxygenated hemoglobin concentration in left and right forehead of the observation group after electrical stimulation was higher than that before electrical stimulation,and the difference was statistically significant(P<0.05).Conclusion Median nerve electrical stimulation combined with computer-assisted cognitive training in the treatment of patients with post-stroke cognitive dysfunction has a significant effect,which can improve the cognitive function of patients,and electrical stimulation can increase the

关 键 词：正中神经电刺激 计算机辅助认知训练 脑卒中后认知功能障碍 临床疗效 认知功能 

分 类 号：R743.9[医药卫生—神经病学与精神病学]