高海拔地区正常人群血常规结果特征分析  

Characteristic analysis of blood routine results for normal population in high altitude area

作　　者：江方正 央金普芝 卓玛德吉 王锋[3] 薛阳阳[4] 叶向红[4] 李百强 童智慧[5] 李维勤[5] JIANG Fang-zheng;YANGJIN Pu-zhi;ZHUOMA De-ji;WAN Feng;XUE Yang-yang;YE Xiang-hong;LI Bai-qiang;TONG Zhi-hui;LI Wei-qin(Department of Critical Care Medicine,Qinhuai Medical District,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,Jiangsu,China;Department of Laboratory Medicine,People's Hospital of Anduo,Nagchu 852000,Tibet,China;Department of Laboratory Medicine,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,Jiangsu,China;Institute of General Surgery,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,Jiangsu,China;Department of Critical Care Medicine,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,Jiangsu,China)

机构地区：[1]东部战区总医院秦淮医疗区重症医学科,南京210002 [2]西藏安多县人民医院检验科,那曲852000 [3]东部战区总医院(原南京军区南京总医院)检验科,南京210002 [4]东部战区总医院(原南京军区南京总医院)全军普通外科研究所,南京210002 [5]东部战区总医院(原南京军区南京总医院)重症医学科,南京210002

出　　处：《医学研究生学报》2021年第9期942-946,共5页Journal of Medical Postgraduates

基　　金：江苏省科技项目(BE2015685);军事医学创新工程(18CXZ040)。

摘　　要：目的血常规分析是临床实验最常用的检测指标,血常规参数标准随海拔增高而发生相应变化,文章对高海拔地区长期居住居民进行血常规结果特征分析,为完善高海拔地区正常人群血常规标准建立提供依据。方法回顾性分析2019年8月9日-9月18日西藏安多县3个乡镇长期居住居民4991名体检者资料,对其血常规结果,按照不同性别、不同年龄段、不同性别不同年龄段等进行特征分析。结果4991名体检者中,男2651例,女2340例,平均年龄(32.57±16.81)岁。4991名检测结果平均水平为:WBC(6.54±1.81)×10^(9)/L,HGB(176.90±24.14)g/L,RBC(5.51±0.62)×10^(12)/L,HCT(51.00±6.73)%,PLT(258.62±70.98)×10^(9)/L。不同性别中HGB、RBC、HCT、MCV、MCH、MCHC、PLT等参数比较的差异有统计学意义(P<0.05)。高原红细胞增多症男性发生率13.51%,高于女性9.57%,差异有统计学意义(P<0.05)。不同年龄段中WBC、HGB、RBC、HCT参数在≤6岁、7~17岁年龄段与18~40岁、41~64岁、≥65岁年龄段比较的差异有统计学意义(P<0.05);PLT参数在各个年龄段比较的差异均有统计学意义(P<0.05)。不同性别的WBC参数在41~64岁年龄段比较的差异有统计学意义(P<0.05);不同性别的HGB、RBC、HCT、PLT四个参数在18~40岁、41~64岁、≥65岁年龄段比较的差异有统计学意义(P<0.05)。结论高海拔地区长期居住居民血常规水平不同于海平面标准大气压水平人群,尤其是HGB、RBC、HCT;这一结果可为完善高海拔地区正常人群血常规标准建立提供依据。Objective Blood routine analysis is the most commonly used detection index in clinical experiments.Blood routine parameter standards change accordingly with the increase of altitude,the blood routine results of long-term residents in high altitude areas were characteristic analyzed to provide a basis for improving the establishment of blood routine standards for normal population in this areas.Methods From August 9,2019 to September 18,2019,the data of 4991 residents in 3 townships of Anduo County,Xizang Province were analyzed retrospectively.All of them were long-term plateau residents and long-term plateau residents.The blood routine results were characteristic analyzed.Results Among 4991 long-term residents in high altitude areas,there were 2651 males and 2340 females,aged from 2 to 90 years(32.57±16.81).Test results show that the leukocyte level was(6.54±1.81)×10^(9)/L,the platelet level was(258.62±70.98)×10^(9)/L,the hemoglobin level was(176.90±24.14)g/L,the male hemoglobin level was(186.05±23.38)g/L,female hemoglobin level was(166.54±20.53)g/L;The number of red blood cells was(5.51±0.62)×10^(12)/L,including(5.74±0.61)×1012/L for male and(5.25±0.53)×1012/L for female.The incidence of male and female high altitude polycytopenia was 13.51%and 9.57%,respectively.The difference between the two groups was statistically significant(P<0.05);The mean hematocrit was(51.00±6.73)%,and the HCT level was(53.37±6.71)%in males and(48.32±5.66)%in females.The blood routine parameters of HGB,RBC,HCT,MCV,MCH,MCHC and PLT of different genders in normal population in high altitude area showed statistically significant differences(P<0.05).There were statistically significant differences in the values of blood routine indexes among normal people of different ages and genders(P<0.05).The WBC parameters in less than or equal 6 years old and 7-17 years old were significantly different from those in adult age(P<0.05).The difference of HGB parameter in the age less than or equal 6 years and 7-17 years group was statist

关 键 词：高海拔地区 健康人群 血常规 特征分析 

分 类 号：R576[医药卫生—消化系统]