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作 者:文艺 吕萍[2] 王辅林 石敏 张欣欣[1] 冯勃[1] WEN Yi;LV Ping;WANG Fulin
机构地区:[1]中国人民解放军总医院耳鼻咽喉头颈外科医学部国家耳鼻咽喉疾病临床医学研究中心聋病教育部重点实验室聋病防治北京市重点实验室,北京100085 [2]川北医学院附属医院耳鼻咽喉头颈外科 [3]中国人民解放军总医院第一医学中心病理科
出 处:《临床耳鼻咽喉头颈外科杂志》2021年第8期748-751,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基 金:解放军总医院医疗大数据研发项目(No:2017MBD-018)。
摘 要:嗜酸细胞腺癌(oncocytic carcinoma, OC)是一种罕见的恶性上皮性肿瘤,亦称恶性嗜酸性腺瘤、恶性大嗜酸粒细胞瘤、大嗜酸粒细胞癌等,可发生于人体的多个器官,如肾、甲状腺、乳腺、涎腺等,原发于舌根者极为罕见。解放军总医院耳鼻咽喉头颈外科收治1例舌根OC患者,经多次手术、放疗和化疗,随访10年无局部复发和全身转移,现总结报告如下。Oncocytic carcinoma of tongue is extremely rare. This paper reports a case of malignant transformation from oncocytic adenoma to oncocytic carcinoma. A 29-year-old man complained of pharyngeal bleeding and swallowing obstruction. The tumor at the base of the tongue was surgically removed and the pathological diagnosis was oncocytic adenoma. After 5 years, the patient found a tumor of the right neck and felt pharyngeal bleeding and swallowing obstruction again. The next year, he was treated with surgery, chemotherapy and radiotherapy, and was diagnosed as oncocytic carcinoma with cervical lymph node metastasis. The patient showed no sign of recurrence until 30 months after the second operation, when tumor of tongue was detected by electronic laryngoscope. Surgery, chemotherapy and radioactive seed implantation were adopted again. Up to now, the follow-up data showed no evidence of recurrence.
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