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出 处:《Blood Science》2020年第4期146-147,共2页血液科学(英文)
基 金:This work has been supported by National Key Research and Development Program(2019YFC0840604);National Natural Science Foundation of China(81730003).
摘 要:Allogeneic hematopoietic stem cell transplantation(allo-HSCT)is one of the most effective methods in the treatment of leukemia and other malignant hematological diseases.However,the occurrence of acute graft-versus-host disease(aGVHD)seriously impairs the survival and prognosis of patients,and the mortality rate of aGVHD is about 10%.^(1) During the development of aGVHD,the initial step consists of injury to the host tissues caused by conditioning regimen.
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