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作 者:Jiamiao Yang Qiaozhi He Linxian Liu Yuan Qu Rongjun Shao Bowen Song Yanyu Zhao
机构地区:[1]Department of Instrument Science and Engineering,School of Electronic Information and Electrical Engineering,Shanghai Jiao Tong University,200240 Shanghai,China. [2]Shanghai Center for Brain Science and Brain-Inspired Technology,200031 Shanghai,China. [3]School of Automation and Software Engineering,Shanxi University,030006 Taiyuan,China. [4]Beijing Advanced Innovation Center for Biomedical Engineering,Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education,School of Engineering Medicine,Beihang University,100191 Beijing,China
出 处:《Light(Science & Applications)》2021年第8期1527-1535,共9页光(科学与应用)(英文版)
基 金:Shanghai Municipal of Science and Technology Project(No.20JC1419500);Foundation of National Facility for Translational Medicine(Shanghai)(No.TMSK-2020-129);Shanghai Pujiang Program(NO.20PJ 1408700);National Natural Science Foundation of China(No.62005007);the Fundamental Research Funds for the Central Universities(Beihang University).
摘 要:Speed and enhancement are the two most important metrics for anti-scattering light focusing by wavefront shaping(WS),which requires a spatial light modulator with a large number of modulation modes and a fast speed of response.Among the commercial modulators,the digital-micromirror device(DMD)is the sole solution providing millions of modulation modes and a pattern rate higher than 20 kHz.Thus,it has the potential to accelerate the process of anti-scattering light focusing with a high enhancement.Nevertheless,modulating light in a binary mode by the DMD restricts both the speed and enhancement seriously.Here,we propose a multi-pixel encoded DMD-based WS method by combining multiple micromirrors into a single modulation unit to overcome the drawbacks of binary modulation.In addition,to efficiently optimize the wavefront,we adopted separable natural evolution strategies(SNES),which could carry out a global search against a noisy environment.Compared with the state-of-the-art DMD-based WS method,the proposed method increased the speed of optimization and enhancement of focus by a factor of 179 and 16,respectively.In our demonstration,we achieved 10 foci with homogeneous brightness at a high speed and formed W-and S-shape patterns against the scattering medium.The experimental results suggest that the proposed method will pave a new avenue for WS in the applications of biomedical imaging,photon therapy,optogenetics,dynamic holographic display,etc.
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