Occurrence and biosynthesis of plant sesterterpenes (C25), a new addition to terpene diversity  

作　　者：Qingwen Chen Jianxu Li Yihua Ma Weiliang Yuan Peng Zhang Guodong Wang 

机构地区：[1]State Key Laboratory of Plant Genomics,Institute of Genetics and Developmental Biology,The Innovative Academy of Seed Design,Chinese Academy of Sciences,Beijing 100101,China [2]National Key Laboratory of Plant Molecular Genetics,CAS Center for Excellence in Molecular Plant Sciences,Chinese Academy of Sciences,Shanghai 200032,China [3]College of Advanced Agricultural Sciences,University of Chinese Academy of Sciences,Beijing,China

出　　处：《Plant Communications》2021年第5期35-44,共10页植物通讯（英文）

基　　金：supported by the Key R&D Program of Shandong Province(grant no.2019JZZY020610);the National Key R&D Program of China(grant no.2018YFA0900600);the National Natural Science Foundation of China(grant no.31970315);the State Key Laboratory of Plant Genomics of China(grant no.SKLPG2016A-13).

摘　　要：Terpenes,the largest group of plant-specialized metabolites,have received considerable attention for their highly diverse biological activities.Monoterpenes(C10),sesquiterpenes(C15),diterpenes(C20),and triterpenes(C30)have been extensively investigated at both the biochemical and molecular levels over the past two decades.Sesterterpenes(C25),an understudied terpenoid group,were recently described by plant scientists at the molecular level.This review summarizes the plant species that produce sesterterpenes and describes recent developments in the field of sesterterpene biosynthesis,placing a special focus on the catalytic mechanism and evolution of geranylfarnesyl diphosphate synthase and sesterterpene synthase.Finally,we propose several questions to be addressed in future studies,which may help to elucidate sesterterpene metabolism in plants.

关 键 词：TERPENE geranylfarnesyl diphosphate synthase metabolic gene clusters specialized metabolites sesterterpene(C25) 

分 类 号：Q94[生物学—植物学]