supported by the Zhejiang Provincial Natural Science Foundation(No.LD22C150001);the Ningbo Key Research and Development Program(No.2022Z179);the Fundamental Research Funds for the Zhejiang Provincial Universities(No.2021XZZX026),China.
Objectives:Terpenes are important volatile organic compounds that impact fruit aroma and flavor quality.Terpene synthases(TPSs)are the key enzymes responsible for the biosynthesis of basic backbone structure of terpen...
supported by the National Key R&D Program of China(No.2023YFC3503902,China);the National Natural Science Foundation of China(Nos.82293681(82293680);82321004,82204234,and 82273822,China);the Guangdong Basic and Applied Basic Research Foundation(Nos.2022B1515120015 and 2021A1515111021,China);the Guangdong Major Project of Basic and Applied Basic Research(No.2023B0303000026,China);the Guangdong-Hong Kong-Macao Universities Joint Laboratory for the Internationalization of Traditional Chinese Medicine(No.2023LSYS002,China);the Guangzhou Key Laboratory of Traditional Chinese Medicine&Disease Susceptibility(No.2024A03J090,China);the Science and Technology Projects in Guangzhou(No.202102070001,China);supported by the high-performance computing platform of Jinan University.
The building blocks-based molecular network(BBMN)strategy was applied to the phytochemical investigation of Cleistocalyx operculatus,leading to the targeted isolation of eighteen novel cinnamoylphloroglucinol-terpene ...
funded by the project“NOCLOT—NuOvi farmaCi anticoaguLanti dalla biOdiversiTàdei meloidi”financed by Regione Lazio(grant nos.A0375-2020-36555 and CUP F85F21003680009);co-funded by MIUR-Italy Grants of Departments of Excellence—L.232/2016—art.1 cc.314–337 awarded to the Department of Science of Roma Tre University(2018–2022 and 2023–2027);supported by the project PON—Ricerca e Innovazione(MUR;Project Code:999900_PON_RTD_A7-G-15023_SCIENZE);support of NBFC to the University of Roma Tre—Department of Science and Sapienza University—Department of Biology and Biotechnologies,“Charles Darwin”,funded by the Italian Ministry of University and Research,PNRR,Missione 4 Componente 2,“Dalla ricerca all’impresa”,Investimento 1.4(Project CN00000033);supported also by Rome Technopole,PNRR grant M-4C-2Inv.1.5 CUP F832B22000040006 to MAB.
Blister beetles(Coleoptera:Meloidae)are currently subdivided into three subfamilies:Eleticinae(a basal group),Nemognathinae,and Meloinae.These are all characterized by the endogenous production of the defensive terpen...
supported by the National Natural Science Foundation of China(Nos.52273118,22275013)。
Owing to the spread of COVID-19,it is difficult to ignore the existence and importance of antimicrobial polymers(AMPs)because most protective appliances are made of polymers.Generally,bacteria prefer hydrophilic compo...
financially supported by the National Natural Science Foundation of China(Grant Nos.:82274603 and 82104946);the Natural Science Foundation of Jiangsu Province,China(Grant No.:BK20210817);the Traditional Chinese Medicine Science and Technology Development Project of Jiangsu Province,China(Project code:QN202008);the Young Scientific and Technological Talents Uplift Project of Jiangsu Association of Integrated Traditional Chinese and Western Medicine,China(Grant No.:JSZXTJ-2024-A05);the Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant No.:KYCX21_3295);the Yangzhou University Graduate Student International Academic Exchange Special Fund Project,China.Thanks for the Graphical abstract drawn。
Adjuvant chemoradiotherapy,molecular targeted therapy,and immunotherapy are frequently employed to extend the survival of patients with advanced gastric cancer(GC).However,most of these treatments have toxic side effe...
supported by the National Natural Science Foundation of China(32260684);the Key Core Agricultural Technology Research Project of XPCC(NYHXGG2023AA602).
To discover novel and efficient compounds against Aphis gossypii Glover,a series of novel terpene ester derivatives containing the structure of bicyclo[2.2.1]heptane were designed and synthesized using tschimganin as t...
funded by the Fujian Agriculture and Forestry University Construction Project for Technological Innovation and Service System of Tea Industry Chain,grant number K1520005A and KH220095A.
Withering is a critical process to form the unique aroma of high-quality white tea.To study the mechanism underlying aroma changes during the white withering,we herein conducted volatile metabolomics and transcriptomi...
supported by the National Natural Science Foundation of China(Grant No.82273879)
Overlook of chiral consideration in transdermal drug delivery increases administrated dose and risk of side effects,decreasing therapeutical effects.To improve the transdermal delivery efficiency of eutomer,this work ...
supported by Australian Research Council centre of Excellence in Synthetic Biology(CE200100029);supported by BioPlatforms Australia through the Commonwealth Government’s National Collaborative Research Infrastructure Strategy(NCRIS).
Hexokinase II(Hxk2)is a master protein in glucose-mediated transcriptional repression signaling pathway.De-grading Hxk2 through an auxin-inducible protein degradation previously doubled sesquiterpene(nerolidol)pro-duc...
financially supported by the National Key R&D Program of China(2018YFA0900600);the National Natural Science Foundation of China(31970315);the Key R&D Program of Shandong Province(2019JZZY020610);the State Key Laboratory of Plant Genomics of China(grant no.SKLPG2016A-13)。
Terpenes are the largest and most diverse class of plant specialized metabolites.Sesterterpenes(C25),which are derived from the plastid methylerythritol phosphate pathway,were recently characterized in plants.In Arabi...