ENANTIOMERS

作品数:123被引量:237H指数:8
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相关领域:理学更多>>
相关作者:顾峻岭傅若农刘会臣侯艳宁史雪岩更多>>
相关机构:北京理工大学浙江大学遵义医学院广州医学院更多>>
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相关基金:国家自然科学基金北京市自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划更多>>
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Chiral resolution of furofuran lignans and their derivatives from the stems of Dendrobium'Sonia'被引量:1
《Chinese Journal of Natural Medicines》2024年第10期937-944,共8页QIU Kaimei QIU Hao XIE Yanqiao ZHANG Siyu ZHANG Qian WANG Zhengtao HAN Zhuzhen YANG Li 
financially supported by the Program of Shanghai Municipal Commission of Health and Family Planning[No.ZY(2021-2023)-0215]。
Five new furofuran lignans and their derivatives,(-)-glaberide I 4-O-β-D-glucopyranoside(1a),(+)-glaberide I 4-O-β-D-glucopyranoside(1b),(+)-glaberide I 7'-ethoxy-4-O-β-D-glucopyranoside(2a),(-)-glaberide I 7'-etho...
关键词:Furofuran lignans Chiral resolution ENANTIOMERS DIASTEREOISOMERS Dendrobium'Sonia' ANTI-INFLAMMATORY 
Organic ferroelastic enantiomers with high Tc and large dielectric switching ratio triggered by order-disorder and displacive phase transition
《Chinese Chemical Letters》2024年第10期228-232,共5页Zhaohong Chen Mengzhen Li Jinfei Lan Shengqian Hu Xiaogang Chen 
supported by the National Natural Science Foundation of China(No.22201120)。
Molecular-based ferroelastics with dielectric switching properties are highly desirable for their applications on microelectronic dielectric switches,sensors,data storage,and so on.However,the current reports mostly f...
关键词:Organic salt ENANTIOMERS FERROELASTIC Dielectric switching PHASETRANSITION 
(+)/(-)-Gerbeloid A,a pair of unprecedented coumarin-based polycyclic meroterpenoid enantiomers from Gerbera piloselloides:Structural elucidation,semi-synthesis,and lipid-lowering activity
《Acta Pharmaceutica Sinica B》2024年第6期2657-2668,共12页Chenxu Zhao Jingrong Li Yue Hu Lingyu Li Meng Yu Yunfeng Huang Tao Zhang Hai Shang Zhongmei Zou 
support from the Natural Sciences Foundation of China(82374035);the CAMS Innovation Fund for Medical Sciences(CIFMS,2022-I2M-1-017,China).
A pair of coumarin-based polycyclic meroterpenoid enantiomers(+)/(-)-gerbeloid A[(+)-1a and(-)-1b]were isolated from the medicinal plant Gerbera piloselloides,which have a unique caged oxatricyclo[4.2.2.0^(3,8)]decene...
关键词:Gerbera piloselloides Natural products Coumarin meroterpenoid Structural elucidation Biomimetic synthesis Lipid-lowering activity 3T3-L1 adipocytes High-fat diet zebrafish model 
Axial enantiomers with donor-regulated TADF feature for multicolor circularly polarized electroluminescence被引量:1
《Science China Chemistry》2024年第6期2039-2045,共7页Chen-Hao Guo Wen-Long Zhao Ke-Ke Tan Wei-Chen Guo Liheng Feng Chuan-Feng Chen Meng Li 
supported by the National Natural Science Foundation of China(22122111,92256304);the Ministry of Science and Technology of China(2022YFA1204401)。
This study optimized the TADF feature of axial chiral enantiomers through precise donor engineering,and multicolor CP-TADFwas achieved in the axial chiral framework.Three pairs of axial enantiomers with donor-regulate...
关键词:axial chirality thermally activated delayed fluorescence circularly polarized luminescence ELECTROLUMINESCENCE organic light-emitting diodes 
Griseofulvin enantiomers and bromine-containing griseofulvin derivatives with antifungal activity produced by the mangrove endophytic fungus Nigrospora sp.QQYB1被引量:1
《Marine Life Science & Technology》2024年第1期102-114,共13页Ge Zou Wencong Yang Tao Chen Zhaoming Liu Yan Chen Taobo Li Gulab Said Bing Sun Bo Wang Zhigang She 
funded by the Guangdong Marine Economy Development Special Project(GDNRC[2022]35,GDNRC[2023]39);the National Natural Science Foundation of China(U20A2001,42276114).
Marine microorganisms have long been recognized as potential sources for drug discovery.Griseofulvin was one of the first antifungal natural products and has been used as an antifungal agent for decades.In this study,...
关键词:Mangrove endophytic fungus Nigrospora sp. GRISEOFULVIN Antifungal activity 
Stereoselective recognition of morphine enantiomers by μ-opioid receptor
《National Science Review》2024年第3期177-185,共9页Yibo Wang Van A.Ngo Xiaohui Wang 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0450102);the Scientific and Technological Innovation 2030(STI2030)-Major Projects(2021ZD0203000(2021ZD0203003));the National Natural Science Foundation of China(91956121,22277118 and 21950410528);the Beijing National Laboratory for Molecular Sciences(BNLMS202108);the Chinese Academy of Sciences Pioneer Hundred Talents Program.
Stereospecific recognition of chiral molecules plays a crucial role in biological systems.The μ-opioid receptor(MOR)exhibits binding affinity towards(-)-morphine,a well-established gold standard in pain management,wh...
关键词:stereoselective recognition thermodynamics and kinetics residence time morphine enantiomers μ-opioid receptor 
Correction: Frequency selective fingerprint sensor: the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT enhancement被引量:6
《PhotoniX》2023年第1期144-144,共1页Jiaming Lyu Shengyuan Shen Lin Chen Yiming Zhu Songlin Zhuang 
Correction: PhotoniX 4, 28 (2023) https://doi.org/10.1186/s43074-023-00108-1 Following publication of the original article [1], the authors reported an error in the spelling of the first author’s last name, the corre...
关键词:CHIRAL error 
Frequency selective fingerprint sensor:the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT enhancement被引量:2
《PhotoniX》2023年第1期188-201,共14页Jiaming Lyu Shengyuan Shen Lin Chen Yiming Zhu Songlin Zhuang 
Basic Science Center Project of the National Natural Science Foundation of China[Grant No.61988102];National Natural Science Foundation of China[Grant No.62275157];Shanghai Shuguang Program[Grant No.18SG44];111 Project[Grant No.D18014].
Chiral enantiomers have different pharmacological and pharmacokinetic characteristics. It is important to strictly detect chiral component for avoiding being harmful to the human body due to side effects. Terahertz (T...
关键词:Chiral enantiomer Frequency-selective fingerprint sensor Multiplexing Absorption induced transparency Fingerprints identification 
A Pair of New Spirocyclic Alkaloid Enantiomers with TrxR Inhibitory Activities Were Isolated from Marine-Derived Aspergillus ruber TX-M4-1被引量:1
《Journal of Ocean University of China》2023年第6期1677-1682,共6页WANG Cong WANG Yufei SUN Jian WANG Shiyi DU Weisheng ZHOU Liman KONG Fandong 
supported by the National Natural Science Foundation of China(No.82204276);the Guangxi Natural Science Foundation(No.2021GXNSFBA075036);the Specific Research Project of Guangxi for Research Bases and Talents(Nos.AD22035018,AD20297036);the 2021 University-Level Scientific Research Projects of Guangxi Minzu University(No.2021MDKJ003);the Talent Scientific Research Initiation Project of Guangxi Minzu University(No.2021KJQD09);the Xiangsi Lake Youth Innovation Team Project of Guangxi Minzu University(No.2021 RSCXSHQN01);the Guangxi Scholarship Fund of Guangxi Education Department.
One new spirocyclic alkaloid,5-isopentenyl-cryptoechinuline D(1),along with 11 known compounds(2–12),were iso-lated from a marine fungus Aspergillus ruber TX-M4-1.The structures of compounds 1–12 were elucidated by ...
关键词:Aspergillus ruber TX-M4-1 spirocyclic alkaloid TrxR inhibitory activity 
Electrochemical Chiral Recognizing Tryptophan Enantiomers Based on Chiral Metal-Organic Framework D-MOF
《Chemical Research in Chinese Universities》2023年第6期976-984,共9页HOU Huipeng TANG Shanshan WANG Wei LIU Miao LIANG Axin XIE Bingteng YI Yue LUO Aiqin 
supported by the National Key R&D Program of China(No.2019YFA0904104).
In this work,an electrochemical chiral sensor of a nanowire-like chiral metal-organic framework/multiwalled carbon nanotube-chitosan/glassy carbon electrode(D-MOF/MWCNTs-CS/GCE)was proposed for the enantiorecognition ...
关键词:Electrochemical chiral sensor Chiral metal-organic framework Multiwalled carbon nanotube-chitosan(MWCNTs-CS) D-MOF Tryptophan(Trp) Potential difference(ΔEp) 
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