funded by the Guangdong Marine Economy Development Special Project(GDNRC[2022]35,GDNRC[2023]39);the National Natural Science Foundation of China(U20A2001,42276114).
Marine microorganisms have long been recognized as potential sources for drug discovery.Griseofulvin was one of the first antifungal natural products and has been used as an antifungal agent for decades.In this study,...
This research received no specific grant from any funding agency in public,commercial,or not-for-profit sectors.
Introduction:Griseofulvin is an antifungal drug belonging to Biopharmaceutical Classification System(BCS class II)having low solubility.Objectives:To formulate,evaluate and enhance the dissolution of poorly water solu...
Pickering emulsions are systems without surfactants, stabilized by solid particles. These emulsions are experiencing a renewed interest, on the one hand, because it is preferable to limit the use of synthetic surfacta...
In an attempt to compare crystal structure determination from powder data and single-crystal data,crystal structure of griseofulvin(C 17 H 17 ClO 6) was tested by both powder and single-crystal X-ray diffraction.Latti...
Supported by the the Natural Science Foundation of China (No.60307003) ;Scientific Research Fund of Zhejiang ProvincialEducation Department (No.20030436)
Chiral molecule C17H17CIO6 was incorporated in MMA by sol-gel process and its optical polarization response was measured. The optical rotatory dispersion was measured with self-manufactured apparatus. The results show...
Griseofulvin (GF) is an antifungal drug whose pharmaceutical activity can be improved by reducing particle size. In this study the rapid expansion of supercritical solution (RESS) was employed to micronize GF.Carbon d...