1972—2016年江苏省启东市结直肠癌死亡趋势分析  

Analysis of Mortality Trend for Colorectal Cancer in Qidong,1972—2016

作　　者：徐源佑 张永辉[1] 丁璐璐[1] 陈永胜[1] 王军 陈建国[1] 朱健[1] XU Yuan-you;ZHANG Yong-hui;DING Lu-lu;CHEN Yong-sheng;WANG Jun;CHEN Jian-guo;ZHU Jian(Qidong People's Hospital&Qidong Liver Cancer Institute,Affiliated Qidong Hospital of Nantong University,Qidong 226200,China)

机构地区：[1]启东肝癌防治研究所/启东市人民医院,南通大学附属启东医院,江苏启东226200

出　　处：《中国肿瘤》2021年第9期665-670,共6页China Cancer

基　　金：南通市卫生健康委员会2019年科研立项课题(QB2019025)。

摘　　要：[目的]探究江苏省启东市1972—2016年结直肠癌死亡率变化趋势,为相关肿瘤的防治工作提供建议。[方法]结直肠癌死亡个案数据来源于1972—2016年启东市肿瘤登记报告。1972—1977年数据使用国际疾病分类(ICD)第8版(ICD-8),1978—1999年数据使用ICD-9,2000—2016年使用ICD-10进行编码。根据中国2000年人口结构以及世界人口结构计算年龄标化死亡率、截缩标化死亡率、累积死亡率和累积死亡风险度等统计指标;使用Joinpoint软件计算平均年度变化百分比(AAPC)。[结果]启东市1972—2016年结直肠癌死亡数以及死亡率逐年增加,45年内结直肠癌死亡人数占全部癌症死亡人数的5.99%,粗死亡率(CR)、中标死亡率(ASRC)和世标死亡率(ASRW)依次为11.72/10万、7.78/10万和7.59/10万,CR、ASRC和ASRW的AAPC依次为4.20%、1.80%和1.90%,45年内结直肠癌的死亡率有明显上升趋势。男性死亡率和死亡率增速均略高于女性。男性CR、ASRC和ASRW依次为11.72/10万、8.01/10万和8.51/10万,女性CR、ASRC和ASRW依次为11.72/10万、7.62/10万和6.85/10万,性别比依次为1.00、1.05和1.24;男性CR、ASRC和ASRW的AAPC依次为4.90%、2.20%和2.40%,女性CR、ASRC和ASRW的AAPC依次为4.20%、1.30%和1.30%;高年龄组死亡率明显高于低年龄组,65岁以上年龄组死亡率增加趋势最为明显。[结论]启东市1972—2016年结直肠癌死亡率均呈现持续上升趋势,男性结直肠癌死亡率和死亡率增长速度均高于女性,高年龄组死亡率和死亡率增长速度明显高于低年龄组。[Purpose] To analyze the changes of the mortality rate of colorectal cancer in Qidong City, Jiangsu Province from 1972 to 2016. [Methods] The data of colorectal cancer deaths from1972 to 2016 were collected from cancer registration. The data from 1972 to 1977, 1978 to 1999 and 2000 to 2016 were coded with ICD-8, ICD-9 and ICD-10, respectively. The crude mortality rate(CR) was calculated;the age-standardized mortality rates were adjusted by Chinese standard population 2000(ASRC) and the Segi’s world standard population(ASRW), respectively. The average annual percentage change(AAPC) was calculated by Joinpoint software. The CR, ASRC and ASRW were 11.72/105, 7.78/105 and 7.59/105, respectively;the AAPC of CR, ASRC and ASRW were 4.20%, 1.80% and 1.90%, respectively. The CR, ASRC and ASRW of males were 11.72/105, 8.01/105 and 8.51/105;those of females were 11.72/105, 7.62/105 and 6.85/105, with a gender ratio of 1.00, 1.05 and 1.24. The AAPC of CR, ASRC and ASRW in males were 4.90%,2.20% and 2.40%, those of females were 4.20%, 1.30%, and 1.30%. The increasing trend of mortality was more markedly in population above 65 years old. [Conclusion] The mortality rate of colorectal cancer has a significant increasing trend in Qidong City from 1972 to 2016, and the mortality rate for males was higher than that of females, and the increasing trend is more marked in high age groups.

关 键 词：结直肠癌 死亡率 趋势分析 江苏 

分 类 号：R735.3[医药卫生—肿瘤]