改良ESD在治疗早期食管癌及癌前病变中的应用价值  

Application Value of Modified ESD in the Treatment of Early Esophageal Cancer and Precancerous Lesions

作　　者：程卫杰[1] 孙旭锐[1] 袁楚明[1] 吴小珑[1] CHENG Weijie;SUN Xurui;YUAN Chuming;WU Xiaolong(Department of Gastroenterology,Jieyang People's Hospital,Jieyang 522000,China)

机构地区：[1]揭阳市人民医院消化内科,广东揭阳522000

出　　处：《临床医学工程》2021年第10期1309-1310,共2页Clinical Medicine & Engineering

基　　金：揭阳市科技计划项目(项目编号:YLWS031)。

摘　　要：目的探讨改良内镜黏膜下剥离术(ESD)治疗早期食管癌及癌前病变的价值。方法选取早期食管癌及癌前病变患者60例,随机分为经典ESD组和改良ESD组各30例,比较两组的疗效、围手术期指标、术后并发症。结果改良ESD组的病变整块切除率、治愈性切除率均显著高于经典ESD组(P<0.05)。改良ESD组的术中出血量、术中止血时间均显著低于经典ESD组(P<0.05)。改良ESD组的术后出血、穿孔、狭窄发生率均显著低于经典ESD组(P<0.05)。结论改良ESD治疗早期食管癌及癌前病变可提高手术效果,降低术后并发症风险。Objective To explore the value of modified endoscopic submucosal dissection(ESD)in the treatment of early esophageal cancer and precancerous lesions.Methods 60 patients with early esophageal cancer or precancerous lesions were selected and randomly divided into the routine ESD group and the modified ESD group,with 30 cases in each group.The efficacy,perioperative indicators and postoperative complications were compared between the two groups.Results The whole resection rate and cure resection rate in the modified ESD group were significantly higher than those in the routine ESD group(P<0.05).The intraoperative blood loss amount and intraoperative hemostatic time in the modified ESD group were significantly lower than those in the routine ESD group(P<0.05).The incidences of postoperative bleeding,perforation and stenosis in the modified ESD group were significantly lower than those in the routine ESD group(P<0.05).Conclusions Modified ESD in the treatment of early esophageal cancer and precancerous lesions can improve the surgical effect and reduce the risk of postoperative complications.

关 键 词：早期食管癌 癌前病变 内镜黏膜下剥离术 疗效 围手术期指标 

分 类 号：R571[医药卫生—消化系统]