Pancreatic paraganglioma diagnosed by endoscopic ultrasoundguided fine needle aspiration: A case report and review of literature  

作　　者：Gandhi Lanke John M Stewart Jeffrey H Lee 

机构地区：[1]Department of Gastroenterology,Hepatology and Nutrition,MD Anderson Cancer Center,Lubbock,TX 79407,United States [2]Pathology-lab Medicine Division,MD Anderson Cancer Center,Houston,TX 77030,United States [3]Department of Gastroenterology,Hepatology and Nutrition,MD Anderson Cancer Center,Houston,TX 77030,United States

出　　处：《World Journal of Gastroenterology》2021年第37期6322-6331,共10页世界胃肠病学杂志（英文版）

摘　　要：BACKGROUND Pancreatic paragangliomas(PPGL)are rare benign neuroendocrine neoplasms but malignancy can occur.PPGL are often misdiagnosed as pancreatic neuroendocrine tumor or pancreatic adenocarcinoma.CASE SUMMARY We reviewed 47 case reports of PPGL published in PubMed to date.Fifteen patients(15/47)with PPGL underwent endoscopic ultrasound-guided fine needle aspiration(EUS-FNA).Only six(6/15)were correctly diagnosed as PPGL.All patients with PPGL underwent surgical resection except three(one patient surgery was aborted because of hypertensive crisis,two patients had metastasis or involvement of major vessels).Our patient remained on close surveillance as she was asymptomatic.CONCLUSION Accurate preoperative diagnosis of PPGL can be safely achieved by EUS-FNA with immunohistochemistry.Multidisciplinary team approach should be considered to bring the optimal results in the management of PPGL.

关 键 词：Pancreatic paraganglioma Endoscopic ultrasound-guided fine needle aspiration Meta-iodobenzylguanidine scan METANEPHRINES GATA-3 IMMUNOHISTOCHEMISTRY Case report 

分 类 号：R735.9[医药卫生—肿瘤]