经阴道三维超声定量评估卵巢储备功能下降及卵巢早衰的价值分析  

Analysis of the value of transvaginal three-dimensional ultrasound in quantitative assessment of decreased ovarian reserve and premature ovarian failure

作　　者：孙婷婷 马桂凤[2] 李晓咪 孟春荣[1] 王鹏[1] SUN Ting-ting;MA Gui-feng;LI Xiao-mi;MENG Chun-rong;WANG Peng(Department of Ultrasound,Weifang Hospital of Traditional Chinese Medicine,Shandong Province,Weifang261021,China;Department of Ultrasound,Affiliated Hospital of Weifang Medical University,Shandong Province,Weifang261021,China)

机构地区：[1]山东省潍坊市中医院超声科,山东潍坊261021 [2]潍坊医学院附属医院超声科,山东潍坊261021

出　　处：《中国当代医药》2021年第28期133-136,共4页China Modern Medicine

基　　金：山东省潍坊市卫生健康委员会立项课题(WFWSJK-2020-345)。

摘　　要：目的探讨经阴道三维超声定量评估在卵巢储备功能下降(DOR)和卵巢早衰(POF)中的应用价值。方法选取2019年1月至2020年11月潍坊市中医院超声科收治的68例疑似DOR患者作为DOR组,70例疑似POF患者作为POF组。另选取同期潍坊市中医院的70例健康体检者作为对照组。三组均采用经阴道三维超声检查,将性激素检查结果作为金标准。比较DOR、POF组左右卵巢和DOR、POF组及对照组的窦卵泡计数(AFC)、卵巢血管化指数(VI)、卵巢体积(OV)、血管化血流指数(VFI)及血流指数(FI)情况,分析经阴道三维超声定量评估对DOR、POF的诊断准确度、敏感度及特异度。结果DOR组和POF组患者的左右卵巢AFC、VI、OV、VFI及FI比较,差异无统计学意义(P>0.05)。DOR组和POF组患者的AFC、VI、OV、VFI及FI水平低于对照组,差异有统计学意义(P<0.05)。POF组患者的AFC、VI、OV、VFI及FI水平低于DOR组,差异有统计学意义(P<0.05)。经阴道三维超声对DOR的诊断准确度、敏感度及特异度分别为92.65%、94.23%、87.50%。经阴道三维超声对POF的诊断准确度、敏感度及特异度分别为95.71%、96.23%、94.23%。结论经阴道三维超声定量评估在诊断DOR及POF中有着重要价值,属于卵巢筛查的一项有效手段。Objective To explore the application value of transvaginal three-dimensional ultrasound quantitative assessment in decreased ovarian reserve(DOR)and premature ovarian failure(POF).Methods From January 2019 to November 2020,68 patients with suspected DOR admitted to the Department of Ultrasound,Weifang Hospital of Traditional Chinese Medicine were selected as the DOR group,and 70 patients with suspected POF as the POF group.In addition,70 healthy subjects from Weifang Hospital of Traditional Chinese Medicine during the same period were selected as the control group.The three groups all used transvaginal three-dimensional ultrasound examinations,and the sex hormone examination results were used as the gold standard.The antral follicle count(AFC),ovarian vascularization index(VI),ovarian volume(OV),vascularized blood flow index(VFI)and blood flow index(FI)were compared between the left and right ovaries of DOR,POF groups and were compared among the three groups,and the diagnostic accuracy,sensitivity and specificity were analyzed of DOR and POF by transvaginal three-dimensional ultrasound in quantitative assessment.Results There were no significant differences in AFC,VI,OV,VFI or FI of the left and right ovaries between the DOR and POF groups(P>0.05).The levels of AFC,VI,OV,VFI and FI in the DOR and POF groups were lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of AFC,VI,OV,VFI and FI in the POF group were lower than those in the DOR group,and the differences were statistically significant(P<0.05).The diagnostic accuracy,sensitivity and specificity of transvaginal three-dimensional ultrasound for DOR were 92.65%,94.23%,and 87.50%,respectively.The diagnostic accuracy,sensitivity and specificity of transvaginal three-dimensional ultrasound for POF were 95.71%,96.23%,and 94.23%,respectively.Conclusion Quantitative assessment of transvaginal three-dimensional ultrasound has important value in the diagnosis of DOR and POF,and it is an effective method for ovari

关 键 词：卵巢早衰 卵巢储备功能下降 三维超声 定量评估 

分 类 号：R737.330[医药卫生—肿瘤]