Nutrition,nutritional deficiencies,and schizophrenia:An association worthy of constant reassessment  

作　　者：Olakunle James Onaolapo Adejoke Yetunde Onaolapo 

机构地区：[1]Behavioural Neuroscience/Neuropharmacology Unit,Department of Pharmacology,Ladoke Akintola University of Technology,Osun State 234,Nigeria [2]Department of Anatomy,Ladoke Akintola University of Technology,Osun State 234,Nigeria

出　　处：《World Journal of Clinical Cases》2021年第28期8295-8311,共17页世界临床病例杂志

摘　　要：Schizophrenia is a mental health disorder that occurs worldwide,cutting across cultures,socioeconomic groups,and geographical barriers.Understanding the details of the neurochemical basis of schizophrenia,factors that contribute to it and possible measures for intervention are areas of ongoing research.However,what has become more evident is the fact that in targeting the neurochemical imbalances that may underlie schizophrenia,the type of response seen with currently available phamacotherapeutic agents does not provide all the answers that are needed.Therefore,the possible contribution of non-pharmacological approaches to schizophrenia management is worthy of consideration.In recent times,research is beginning to show nutrition may play a possibly significant role in schizophrenia,affecting its development,progression and management;however,while attempts had been made to examine this possible relationship from different angles,articles addressing it from a holistic point of view are not common.In this review,we examine existing scientific literature dealing with the possible relationship between nutrition and schizophrenia,with a view to elucidating the impact of diet,nutritional deficiencies and excesses on the aetiology,progression,management and outcome of schizophrenia.Secondly,the effect of nutritional supplements in prevention,as sole therapy,or adjuncts in schizophrenia management are examined.

关 键 词：Diet Brain Mental health Nutritional psychiatry PSYCHOSIS Schizophrenia spectrum disorders 

分 类 号：R749.3[医药卫生—神经病学与精神病学]