微创胸腹腔镜联合食管癌根治术的治疗效果  

Treatment effect of minimally invasive thoracolaparoscopy combined with radical resection of esophageal cancer

作　　者：冯光强[1] 高兴才[1] 陈涛 FENG Guangqiang;GAO Xingcai;CHEN Tao(Department of Cardiothoracic Surgery,the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)

机构地区：[1]郑州大学第五附属医院心胸外科,郑州450000

出　　处：《癌症进展》2021年第17期1774-1777,共4页Oncology Progress

摘　　要：目的观察微创胸腹腔镜联合食管癌根治术的治疗效果。方法将96例行食管癌根治术的患者根据手术方法分为观察组(n=70)和对照组(n=26),观察组实施胸腹腔镜联合食管癌根治术,对照组应用传统小切口食管癌根治术。比较两组患者的手术一般情况、氧分压、并发症及预后情况。结果观察组患者手术时间、术中出血量、淋巴结清扫数目、术后住院时间均明显低于对照组(P﹤0.01)。术后6、72 h,观察组患者的氧分压均明显高于对照组,差异均有统计学意义(P﹤0.01)。观察组患者并发症总发生率为28.57%(20/70),明显低于对照组的61.54%(16/26),差异有统计学意义(χ^(2)=21.489,P=0.000)。观察组患者术后淋巴结转移率、复发率、二次手术发生率均明显低于对照组,术后生活质量评分、6个月内生存率均明显高于对照组,差异均有统计学意义(P﹤0.01)。结论微创胸腹腔镜联合食管癌根治术相比传统小切口食管癌根治术具有独特的优势,其安全可靠、微创、恢复快,值得在临床上推广使用。Objective To observe the treatment effect of minimally invasive thoracolaparoscopy combined with radi-cal resection of esophageal cancer.Method A total of 96 patients undergoing radical esophagectomy were divided into the observation group(n=70,treated with thoracolaparoscopy combined with radical resection of esophageal cancer)and control group(n=26,treated with traditional small incision radical resection of esophageal cancer).The general condi-tions of operation,oxygen partial pressure,complications and prognosis were compared between the two groups.Result The operation time,intraoperative blood loss,number of lymph node dissection and postoperative hospitalization time in the observation group were significantly lower than those in the control group(P<0.01).After operation 6 h and 72 h,the oxygen partial pressures in the observation group were significantly higher than those in control group(P<0.01).The total rate of complications in the observation group was 28.57%(20/70)significantly lower than 61.54%(16/26)in the control group,the difference was statistically significant(χ^(2)=21.489,P=0.000).The postoperative lymph node metastasis rate,re-currence rate and rate of second operation in the observation group were significantly lower than those in control group,the postoperative quality of life score and 6-month survival rate were significantly higher than those of the control group,the differences were statistically significant(P<0.01).Conclusion Compared with traditional small incision radical re-section of esophageal cancer,minimally invasive thoracolaparoscopy combined with radical resection of esophageal can-cerhas unique advantage,it is safe and reliable,minimally invasive and fast recovery,so it is worthy of clinical application.

关 键 词：微创 胸腹腔镜 食管癌根治术 

分 类 号：R735.1[医药卫生—肿瘤]