消除子宫颈癌之HPV疫苗应用广东专家共识  

Guangdong expert consensus on HPV vaccine application to eliminate cervical cancer

作　　者：广东省预防医学会宫颈癌防治专业委员会 李小毛[2] 万璟[2] 王焕[2] 杨越波[2] 张宇[2] Cervical Cancer Prevention and Treatment Committee of Guangdong Preventive Medicine Association;Li Xiaomao(不详;The 3rd Affiliated Hospital of Sun Yat-Sen University)

机构地区：[1]不详 [2]中山大学附属第三医院

出　　处：《中国医师杂志》2021年第9期1303-1315,共13页Journal of Chinese Physician

摘　　要：子宫颈癌是常见的严重威胁女性健康的恶性肿瘤,实施对目标人群人乳头瘤病毒(HPV)疫苗接种是实现消除子宫颈癌目标的重要措施之一。本共识专家组一致认为HPV疫苗是安全有效的,接种疫苗是子宫颈癌防控的有效策略,并结合国内外接种经验和广东省实际情况的基础上,提出了一系列涉及多部门、多学科全社会共同参与的具体措施和咨询建议供有关部门决策参考,以利于提高优先推荐人群HPV疫苗接种率。具体包括:加强公众及医务人员子宫颈癌防控知识的健康科普教育,增强疾病预防意识,以增加疫苗信心,提高接种意愿;逐步将HPV疫苗纳入我国免疫规划程序,通过带量采购并大幅降低疫苗价格,多渠道增加支付途径,以提高HPV疫苗的可负担性;推荐低年龄段女性为优先接种人群,建议青春前期人群全程接种2剂次,多种渠道保障重点目标人群的HPV疫苗供应,以提高优先接种人群疫苗的可及性;丰富疫苗接种场景,让受种者获得更好的接种体验,利用现代信息技术改善接种便利性;建立健全HPV疫苗接种与子宫颈癌筛查信息化网络互联互通,推进医联体专科联盟建设,促进区域内的三级预防联动工作;建设真实世界研究信息管理大数据研究平台,加强上市后的临床研究,探讨优化筛选更具有可操作性的子宫颈癌防控策略,为加速实现消除子宫颈癌目标提供科学依据。Cervical cancer is a common malignant tumor that seriously threatens women′s health.Human papilloma virus(HPV)vaccination in target populations is an important measure to achieve the goal of eliminating cervical cancer.This expert consensus has agreed on the effectiveness and safety of HPV vaccination,which is an effective strategy for cervical cancer prevention and control.Based on domestic and foreign experience of HPV vaccination and the specific circumstance in Guangdong Province,a series of concrete suggestions are made for decision-making consulation to improve the coverage of HPV vaccination of primary target population.In the consensus,we propose to strengthen the public and medical staffs′health science education for cervical cancer prevention and control to enhance vaccination confidence and health awareness,and increase the vaccination willingness.And gradually incorporating HPV vaccine into the immunization plan,reducing vaccine prices through purchasing in large quantities,and increasing multi-channel payment channels are recommended to increase the affordability of HPV vaccines.Women in low age group are recommended to be the priority group for vaccination.In order to ensure the accessibility of vaccines for priority groups,it is recommended that the pre-adolescent groups be given two doses throughout the course of vaccination.We suggest to enrich the vaccination scenarios,so that the recipient can get a better vaccination exprience.And information technology would be used to improve the convenience of vaccination.Establishing HPV vaccination and cervical cancer screening information interconnection network are suggested to promote the construction of specialist alliances and the three-level prevention work.Besides,we also need to build a real-world research information management data research platform,and strengthen the post-marketing clinical research to optimize the feasible strategies for cervical cancer prevention and control.We hope all the above mesures may provide scientific evidence fo

关 键 词：子宫颈癌 人乳头瘤病毒 疫苗 专家共识 

分 类 号：R737.33[医药卫生—肿瘤]