基于微信平台信息共享对颈动脉易损斑块患者预后的影响  

The impact of information sharing based on WeChat platform on the prognosis of patients with vulnerable carotid plaques

作　　者：陈薇[1] 应君芳[2] 寻华音[3] 王凤[4] CHEN Wei;YINGJunfang;XUN Huayin;WANG Feng(Service Center,Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University,Taizhou317000,China;Department of Neurosurgery,Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University,Taizhou317000,China;Department of Blood Purification,Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University,Taizhou317000,China;Department of Neurology,Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University,Taizhou317000,China)

机构地区：[1]浙江省台州医院服务中心,浙江台州317000 [2]浙江省台州医院神经外科,浙江台州317000 [3]浙江省台州医院血液净化中心,浙江台州317000 [4]浙江省台州医院神经内科,浙江台州317000

出　　处：《中国现代医生》2021年第24期122-125,共4页China Modern Doctor

基　　金：浙江省医药卫生科技计划项目(2021RC141)。

摘　　要：目的探讨基于微信平台信息共享对颈动脉易损斑块患者预后的影响。方法选取2018年6月至2020年6月我院收治的颈动脉易损斑块患者85例作为本研究对象。采用随机数字表法将本研究对象分为研究组43例与对照组42例。对照组患者采用他汀类药物进行治疗,研究组在对照组药物治疗的基础上,给予基于微信信息共享的干预措施,统计比较干预前后各组的易损斑块的面积大小及斑块数量的变化情况,比较组间干预前后颈总动脉平均内中膜厚度(IMT),比较各组干预前后的血脂变化情况。结果干预6个月后,两组易损斑块面积大小均较干预前变小,差异有统计学意义(P<0.05);干预前,两组易损斑块面积比较,差异无统计学意义(P>0.05),干预6个月后,研究组易损斑块面积小于对照组,差异有统计学意义(P<0.05);干预后6个月,研究组斑块消失数量多于对照组,差异有统计学意义(P<0.05)。干预6个月后,两组IMT均较干预前降低,差异有统计学意义(P<0.05);干预前,两组IMT比较,差异无统计学意义(P>0.05),干预6个月后,研究组IMT低于对照组,差异有统计学意义(P<0.05)。干预后6个月,两组三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)均较干预前降低,高密度脂蛋白胆固醇(HDL-C)较干预前升高,差异均有统计学意义(P<0.05);干预前,两组TG、TC、LDL-C、HDL-C比较,差异均无统计学意义(P>0.05);干预后6个月,研究组TG、TC、HDL-C低于对照组,HDL-C高于对照组,差异均有统计学意义(P<0.05)。结论针对颈动脉易损斑块患者,在药物治疗的基础上给予基于微信信息共享的干预措施,可以改善治疗效果,降低不良心血管事件的发生,值得在临床上推广应用。Objective To explore the impact of information sharing based on WeChat platform on the prognosis of patients with vulnerable carotid plaques.Methods Ninety-five patients with vulnerable carotid plaques admitted to our hospital from June 2018 to June 2020 were selected as the study objects and divided into two groups by random number table method,namely 43 cases in the study group and 42 cases in the control group.The control group was treated with statins,while the study group was given WeChat information sharing based intervention measures on the basis of the same drug treatment as the control group.The changes in the area of vulnerable plaques and the number of plaques in each group before and after the intervention were statistically compared.Meanwhile,the mean intima-media thickness(IMT)in the common carotid artery and the changes in blood lipid before and after the intervention were compared between the two groups.Results After 6 months of intervention,the areas of vulnerable plaques in the two groups were smaller than those before the intervention,with statistically significant difference(P<0.05).Before the intervention,there was no statistically significant difference in the areas of vulnerable plaques between the two groups(P>0.05).After 6 months of intervention,the areas of vulnerable plaques in the study group were smaller than those in the control group,with statistically significant difference(P<0.05).During 6 months after the intervention,the number of plaques in the study group disappeared more than that in the control group,with statistically significant difference(P<0.05).The IMT in the two groups after 6 months of intervention was lower than that before the intervention,with statistically significant difference(P<0.05).The IMT difference between the two groups was not statistically significant before the intervention(P>0.05).The IMT of the study group after 6 months of intervention was lower than that of the control group,with statistically significant difference(P<0.05).The levels of triacylglyc

关 键 词：颈动脉易损斑块 颈动脉粥样斑块 脑梗死 微信平台 信息共享 

分 类 号：R743.3[医药卫生—神经病学与精神病学]