微生物多糖的发酵生产及其在创面敷料中的应用  

Fermentation Production of Microbial Polysaccharides and It’s Application in Wound Dressings

作　　者：涂迎盈 李凌晖 赵新宇 蒋曙光[1] TU Yingying;LI Linghui;ZHAO Xinyu;JIANG Shuguang(School of Pharmacy,China Pharmaceutical University,Nanjing 211198,China)

机构地区：[1]中国药科大学药学院,南京211198

出　　处：《中国现代应用药学》2021年第17期2185-2192,共8页Chinese Journal of Modern Applied Pharmacy

摘　　要：微生物多糖是细菌、真菌等微生物在代谢过程中产生的高分子碳水化合物。微生物多糖结构功能多样,生产周期短,质量不受地理环境影响,可通过生物发酵技术实现工业化生产,在化工、食品、医药等领域应用前景广阔。本文综述了黄原胶、透明质酸和细菌纤维素等微生物多糖的理化性质、发酵生产及创面应用等方面的研究进展,以期推动微生物多糖在创面应用中的深入研究,扩大微生物多糖的市场应用范围。Microbial polysaccharides are high-molecular carbohydrates produced by microorganisms such as bacteria and fungi in the metabolic process. Microbial polysaccharides have diverse structures and functions, in addition, the production cycle of microorganisms is short, and the geographical environment will not affect the growth of microorganisms. What’s more, the industrial production can be achieved through biological fermentation technology. Hence, it has a very broad application prospects in the fields of chemical industry, food, and medicine. This review summarizes the research progress of microbial polysaccharides such as xanthan gum, hyaluronic acid and bacterial cellulose in their physical and chemical properties, fermentation and wound application. Hoping to promote the in-depth study of microbial polysaccharides in wound and expand the market application of microbial polysaccharides.

关 键 词：创面敷料 微生物多糖 黄原胶 透明质酸 细菌纤维素 发酵生产 

分 类 号：R943[医药卫生—药剂学]