探讨口腔唾液胃蛋白酶检测对咽喉反流患者的应用  

To explore the application of the detection of stomatological saliva pepsin in patients with reflux of throat and throat

作　　者：王茜 Wang Qian(Department of Integrated,Yuehu branch of Ningbo stomatological hospital,Ningbo,Zhejiang,315000,China)

机构地区：[1]宁波口腔医院月湖分院综合科,浙江宁波315000

出　　处：《中国医学文摘（耳鼻咽喉科学）》2021年第5期95-97,共3页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：目的探析口腔唾液胃蛋白酶检测在咽喉反流患者诊断中的应用效果。方法选取我院2019年12月至2020年12月期间收治的58例咽喉反流患者作为研究对象,所有患者均于1天内接受3次口腔唾液胃蛋白酶检测,记录并对比患者不同时间(晨起漱口前、午餐后1h与症状显著时)胃蛋白酶阳性率与胃蛋白酶水平。结果患者晨起漱口前胃蛋白酶水平为13.79%,午餐后1h胃蛋白酶阳性率为8.62%,症状显著时蛋白酶水平为43.10%,比较发现患者症状显著时胃蛋白酶阳性率高于晨起漱口前、午餐后1h(P<0.05)。患者晨起漱口前、症状显示时胃蛋白酶水平显著低于午餐后1h(P<0.05)。结论在咽喉反流患者诊断中应用口腔唾液胃蛋白酶检测,有助于医护人员了解患者不同时间的胃蛋白酶水平,并根据胃蛋白酶检测结果,对其病情进行判断。Objective To explore the application effect of oral saliva pepsin detection in the diagnosis of patients with laryngopharyngeal reflux.Methods 58 patients with laryngopharyngeal reflux in our hospital from December 2019 to December 2020 were selected as the research objects,All patients were tested with oral salivary pepsin three times in one day,The positive rate of pepsin and the level of pepsin were recorded and compared at different time(before gargling in the morning,1 hour after lunch and when symptoms were significant).Result The pepsin level before gargling was 13.79%,One hour after lunch,the positive rate of pepsin was 8.62%,The protease level was 43.10%when the symptoms were significant,It was found that the positive rate of pepsin in patients with significant symptoms was higher than that before gargling in the morning and 1 hour after lunch(P<0.05).The pepsin level of patients before gargling in the morning and at symptom presentation was significantly lower than that at 1 hour after lunch(P<0.05).Conclusion In the diagnosis of patients with laryngopharyngeal reflux,the application of oral saliva pepsin detection has the following advantages.It is helpful for medical staff to analyze the pepsin test results,To judge the condition.

关 键 词：口腔唾液 胃蛋白酶 咽喉反流 

分 类 号：R78[医药卫生—口腔医学]