腹腔镜手术和开腹手术治疗子宫内膜癌的效果评价  

Evaluation of the effects of laparoscopic surgery and laparotomy in treatment of endometrial cancer

作　　者：黄萍萍 温坦华 侯蕊 黎燕霞[1] 王薇[1] 范良生[1] HUANG Ping-Ping;WEN Tan-Hua;HOU Rui(Department of Obstetrics and Gynecology,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510120,China)

机构地区：[1]广州医科大学附属第一医院妇产科,广东广州510120

出　　处：《中国妇幼保健》2021年第19期4412-4415,共4页Maternal and Child Health Care of China

基　　金：国家自然科学基金资助项目(81302249);广东省医学科研基金项目(A2018065)。

摘　　要：目的比较腹腔镜手术和开腹手术治疗子宫内膜癌的效果。方法选取2009-2018年广州医科大学附属第一医院收治的193例确诊为子宫内膜癌的患者,分为开腹组(64例)和腹腔镜组(129例)。开腹组实施开腹手术,腹腔镜组实施腹腔镜手术。比较患者术中指标、术后并发症及随访情况。结果开腹组患者平均术中出血量、输血人数、术后平均恢复肛门排气时间、术后平均盆腔引流量及术后平均住院时间分别为(240.00±323.74)ml、12例、(2.23±0.87)d、(232.80±307.42)ml及(10.13±3.45)d,腹腔镜组患者平均术中出血量、输血人数、术后平均恢复肛门排气时间、术后平均盆腔引流量及术后平均住院时间分别为(139.84±136.97)ml、10例、(1.90±0.69)d、(287.10±435.27)ml及(9.43±4.07)d,两种比较差异均有统计学意义(t=-2.206,χ^(2)=5.123,t=-2.633,t=-2.250,t=-1.980,均P<0.05)。腹腔镜组术后并发症总发生率为1.55%(2例),开腹组术后并发症总发生率为9.38%(6例),两组比较差异有统计学意义(χ^(2)=4.769,P=0.029)。在随访期内,腹腔镜组有3例死亡,开腹组有3例死亡,两组总体生存率比较差异无统计学意义(Log-rank=0.844,P=0.358)。结论与开腹手术比较,腹腔镜手术治疗子宫内膜癌的安全性和疗效较好。Objective To compare the effects of laparoscopic surgery and laparotomy in treatment of endometrial cancer. Methods From 2009 to 2018,193 patients diagnosed as endometrial cancer were selected from the First Affiliated Hospital of Guangzhou Medical University, then they were divided into laparotomy group(64 cases) and laparoscopic surgery group(129 cases),the patients in control group were treated with laparotomy, and the patients in laparoscopic surgery group were treated with laparoscopic surgery, the intraoperative indexes, postoperative complications, and follow-up situations in the two groups were compared. Results The average amount of intraoperative hemorrhage, the number of cases of blood transfusion, the average recovery time of postoperative anal exhausting, the average postoperative pelvic drainage volume, and the average postoperative hospitalization time in laparotomy group were(240.00±323.74)ml, 12,(2.23±0.87)days,(232.80±307.42)ml, and(10.13±3.45)days, respectively;the average amount of intraoperative hemorrhage, the number of cases of blood transfusion, the average recovery time of postoperative anal exhausting, the average postoperative pelvic drainage volume, and the average postoperative hospitalization time in laparoscopic surgery group were(139.84±136.97)ml, 10,(1.90±0.69)days,(287.1±435.27)ml, and(9.43±4.07)days, respectively, there were statistically significant differences between the two groups(t=-2.206,χ^(2)=5.123,t=-2.633,t=-2.250,t=-1.980,P<0.05). The total incidence rate of postoperative complications in laparoscopic surgery group was 1.55%(2 cases),the total incidence rate of postoperative complications in laparotomy group was 9.38%(6 cases), there was statistically significant difference(χ^(2)=4.769,P=0.029). During follow-up, 3 cases died in laparoscopic surgery group, and 3 cases died in laparotomy group, there was no statistically significant difference(Log-rank=0.844,P=0.358). Conclusion Compared with laparotomy, the safety and curative effect of laparoscopic surgery i

关 键 词：开腹手术 腹腔镜手术 子宫内膜癌 疗效 

分 类 号：R737.33[医药卫生—肿瘤]