质子泵抑制剂治疗反流性咽喉炎的临床疗效及其安全性  

The clinical efficacy and safety of proton pump inhibitors in the treatment of reflux pharyngitis

作　　者：吴琼 区洁芳[1] 夏惠仪 王影[1] Wu Qiong;Ou Jiefang;Xia Huiyi;Wang Ying(Department of Gastroenterology,People’s Hospital of Gaoming District,Foshan,Guangdong,528500,China)

机构地区：[1]佛山市高明区人民医院消化内科,广东佛山528500

出　　处：《中国医学文摘（耳鼻咽喉科学）》2021年第4期139-140,151,共3页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：目的探析反流性咽喉炎采取质子泵抑制剂治疗的临床效果。方法选取2019年8月~2020年11月于本院耳鼻咽喉科就诊的反流性咽喉炎患者,统计72例,以随机数字表法分组,即对照组(n=36)和研究组(n=36),对照组采取常规疗法,基于此基础,研究组采取质子泵抑制剂,总结两组效果。结果研究组有效率与对照组比明显提高(P<0.05);研究组反流症状、体征指数低于对照组(P<0.05);在不良反应上,两组无显著差异(P>0.05)。结论反流性咽喉炎采取质子泵抑制剂效果理想,可纠正反流及体征指数,提高临床疗效,其不良反应少,安全性较高。Objective To analyze the clinical effect of proton pump inhibitors for reflux pharyngitis.Methods Selected reflux pharyngitis patients who were treated in the Otorhinolaryngology Department of our hospital from August 2019 to November 2020,counted 72 cases,and grouped them by random number table,namely the control group(n=36)and the study group(n=36),the control group took conventional therapy.Based on this foundation,the study group took proton pump inhibitors to summarize the effects of the two groups.Results The effective rate of the study group was significantly higher than that of the control group(P<0.05);the reflux symptoms and signs of the study group were lower than those of the control group(P<0.05);there was no significant difference between the two groups in terms of adverse reactions(P>0.05).Conclusion Proton pump inhibitors for reflux pharyngitis have an ideal effect,can correct reflux and physical index,improve clinical efficacy,and have fewer adverse reactions and higher safety.

关 键 词：反流性咽喉炎 质子泵抑制剂 不良反应 效果 

分 类 号：R57[医药卫生—消化系统]