抑郁障碍伴躯体疼痛的炎性机制相关研究进展  

Research progress on inflammatory mechanism of depressive disorder with somatic pain

作　　者：刘莉[1] 叶兰仙[1] Liu Li;Ye Lanxian(Department of Mental Healthy the Second Hospital of Lanzhou University,Lanzhou 730030,China)

机构地区：[1]兰州大学第二医院心理卫生科,730030

出　　处：《神经疾病与精神卫生》2021年第9期647-651,共5页Journal of Neuroscience and Mental Health

摘　　要：在临床上,超过半数的抑郁障碍患者伴有躯体疼痛,而炎性介质在两者共同的病理生理过程中发挥着重要作用.外周细胞因子受到刺激后还可产生其他可通过血脑屏障的炎性介质,从而诱发中枢炎症.现主要阐述抑郁障碍伴躯体疼痛相关的炎性细胞因子的研究进展.Clinically,more than half of patients with depressive disorder have somatic pain,and inflammatory mediators play an important role in the common pathophysiological process of them.Peripheral cytokines can also produce other inflammatory mediators that can pass through the blood-brain barrier after being stimulated,thus inducing the occurrence of central inflammation.This article mainly describes the research progress of inflammatory cytokines related to depressive disorder with somatic pain.

关 键 词：抑郁障碍 躯体疼痛 炎症 细胞因子类 综述 

分 类 号：R749.4[医药卫生—神经病学与精神病学]