2021年世界卫生组织中枢神经系统肿瘤分类(第五版)整合及分层诊断解读  

Integrated and layered diagnoses in the 2021 WHO Classification of Tumors of the Central Nervous System(fifth edition)

作　　者：杨学军[1] 陈宏 李佳博 孙翠云[5] 尹洪芳[2] YANG Xue-jun;CHEN Hong;LI Jia-bo;SUN Cui-yun;YIN Hong-fang(Department of Neurosurgery,Beijing Tsinghua Changgung Hospital,Affiliated Hosptital of Tsinghua University,Beijing 102218,China;Department of Pathology,Huashan Hospital,Fudan University,Shanghai 200040,China;Department of Neurosugery,Tianjin Medical University General Hospital,Tianjin 300052,China;Department of Neuropathology,Tianjin Medical University General Hospital,Tianjin 300052,China;Department of Pathology,Beijing Tsinghua Changgung Hospital,Affiliated Hosptital of Tsinghua University,Beijing 102218,China)

机构地区：[1]清华大学附属北京清华长庚医院神经外科,102218 [2]清华大学附属北京清华长庚医院病理科,102218 [3]复旦大学附属华山医院病理科,上海200040 [4]天津医科大学总医院神经外科,300052 [5]天津医科大学总医院神经病理科,300052

出　　处：《中国现代神经疾病杂志》2021年第9期764-768,共5页Chinese Journal of Contemporary Neurology and Neurosurgery

摘　　要：中枢神经系统肿瘤整合及分层诊断的提出是基于分子信息在中枢神经系统肿瘤分类中重要性日益增加的需要。2021年世界卫生组织中枢神经系统肿瘤分类(第五版,简称新版肿瘤分类)在第四版修订版的基础上,为展现全部可用的诊断信息,提出诊断报告需第一层给出整合诊断,然后依次为组织病理学分类、WHO分级和分子信息。本文针对新版肿瘤分类的整合及分层诊断要求进行解读。The integrated and layered diagnoses of central nervous system tumors is based on the growing importance of molecular information in the classification of central nervous system tumors.The 2021 WHO Classification of Tumors of the Central Nervous System(fifth edition)updated the integrated and layered diagnoses methods based on the previous version of the WHO tumors classification(fourth revised version).Layered report feature an integrated diagnosis at the top,followed by layers that display histopathological classification,WHO classification and molecular information.This review mainly focuses on the interpretation of the integrated diagnosis and grading of central nervous system tumors in the new edition tumors classification.

关 键 词：中枢神经系统肿瘤 指南 世界卫生组织 诊断 病理学 分子 综述 

分 类 号：R739.4[医药卫生—肿瘤]