利用中国仓鼠制备疾病模型的优势与进展  

Advantages and Progress of Using Chinese Hamsters to Construct Disease Models

作　　者：高继萍 陈朝阳 轩瑞晶 张锐虎 宋国华 GAO Jiping;CHEN Zhaoyang;XUAN Ruijing;ZHANG Ruihu;SONG Guohua(Laboratory Animal Center of Shanxi Medical University,Shanxi Key Laboratory of Experimental Animal Science and Human Disease Animal Models,Taiyuan 030001,China;Mental Health Hospital Affiliated to Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学实验动物中心,实验动物与人类疾病动物模型山西省重点实验室,太原030001 [2]山西医科大学附属精神卫生医院,太原030001

出　　处：《实验动物与比较医学》2021年第5期392-398,共7页Laboratory Animal and Comparative Medicine

基　　金：国家自然科学基金资助项目(31970513);山西省实验动物资源共享服务平台项目(201605D121019)。

摘　　要：中国仓鼠是具有中国特色的实验动物,在医学和生物学等实验研究中占有重要地位,广泛用于遗传学、传染病学和组织培养等生命科学研究,尤其是在糖尿病与口腔癌等动物模型及机制研究方面独具特色。本文就中国仓鼠自被开发以来在疾病动物模型中的应用研究进行综述,探讨中国仓鼠在生物医学研究中的作用与面临的问题。Chinese hamsters are experimental animals originally from China.They play an important role in experimental research on medicine and biology.They are widely used in life science research,such as genetics,infectious diseases,tissue culture,especially in animal models and mechanism research,such as diabetes and oral cancer.This paper reviews the relevant applied studies of Chinese hamsters in disease animal models since its development,and discusses the advantages and problems associated with the use of these animals in biomedical research.

关 键 词：中国仓鼠 生物医学 动物模型 

分 类 号：Q95-33[生物学—动物学] R-332[医药卫生]