CT及磁共振成像联合血清糖类抗原125诊断卵巢良恶性肿瘤的临床价值  

Clinical Value of CT and Magnetic Resonance Imaging Combined with Serum Carbohydrate Antigen 125 in the Diagnosis of Benign and Malignant Ovarian Tumors

作　　者：黄蓉[1] 饶友鹏[1] 黄小连 HUANG Rong;RAO Youpeng;HUANG Xiaolian(The Second Hospital of Longyan City,Fujian Province,Longyan 364000,China)

机构地区：[1]福建省龙岩市第二医院,福建龙岩364000

出　　处：《中国医药指南》2021年第27期37-39,共3页Guide of China Medicine

摘　　要：目的观察CT及磁共振成像联合血清糖类抗原125(CA125)诊断卵巢良恶性肿瘤的效果。方法选取72例患者术前均接受CT、MRI、血清CA125检查,之后均接受手术及病理组织学检查。将CT、MRI、血清CA125单独检查结果、两两联合检查结果、3种方式联合检查结果与病理组织学检查结果进行比较,统计72例患者卵巢肿瘤良性、恶性检出情况,比较不同检查方式对卵巢良恶性肿瘤的诊断价值,具体项分为真阳性、假阳性、假阴性、真阴性、灵敏度、特异度等。结果病理检查结果显示,72例卵巢肿瘤患者中,共有31例确诊为恶性,41例为良性。其中,CT、MRI、CA125、CT+MRI、CT+CA125、MRI+CA125、3种方式联合检查下,恶性卵巢肿瘤检出例数分别为22例、24例、18例、25例、23例、24例、29例。针对72例卵巢肿瘤患者恶性肿瘤检出的灵敏度分别为70.97%、77.42%、58.06%、80.65%、74.19%、77.42%、93.55%,特异度分别为85.37%、90.24%、92.68%、92.68%、85.37%、87.80%、97.56%。结论CT、磁共振、血清CA125均为临床常见的检查方式,但单独或两两联合应用于卵巢肿瘤疾病诊断时,与病理检查结果相比,具有一定的差异,可能造成误诊或漏诊。而将3种方式联合使用时,检查结果与病理结果之间的差异会大幅度缩小,检查准确程度(卵巢肿瘤良性、恶性)十分精确。因此,3种方式联用的临床价值较高。Objective To observe the effect of CT and magnetic resonance imaging combined with serum carbohydrate antigen 125 in the diagnosis of benign and malignant ovarian tumors.Methods A total of 72 patients underwent CT,MRI and serum CA125 before operation,and then underwent operation and histopathology.The results of CT,MRI and serum CA125 were compared with those of histopathology,and the detection of benign and malignant ovarian tumors in 72 patients were counted.Compare the diagnostic value of different examination methods for benign and malignant ovarian tumors.The specific items are divided into true Yang,false Yang,false Yin,true Yin,sensitivity,specificity,etc.Results Pathological examination showed that among 72 patients with ovarian tumors,31 were diagnosed as malignant and 41 were benign.Among them,under the combined examination of CT,MRI,CA125,CT+MRI,CT+CA125 and MRI+CA125,the detected cases of malignant ovarian tumors were 22,24,18,25,23,24 and 29 respectively.The sensitivity of detecting malignant tumors in 72 patients with ovarian tumors were 70.97%,77.42%,58.06%,80.65%,74.19%,77.42%and 93.55%respectively,and the specificity were 85.37%,90.24%,92.68%,92.68%,85.37%,87.80%and 97.56%respectively.Conclusion CT,MRI and serum CA125 are common clinical examination methods,but when applied alone or in combination,they have certain differences compared with pathological examination results,which may lead to misdiagnosis or missed diagnosis.When the three methods are combined,the difference between the examination results and pathological results will be greatly reduced,and the examination accuracy(benign and malignant differentiation of ovarian tumors)will be very accurate.Therefore,the combination of the three methods has high clinical value.

关 键 词：卵巢肿瘤 CT扫描 磁共振 血清CA125 良恶性 

分 类 号：R737.31[医药卫生—肿瘤]