多囊卵巢综合征合并非酒精性脂肪性肝病的危险因素  

Risk factors for polycystic ovary syndrome with nonalcoholic fatty liver disease

作　　者：王东旭[1] 邢川 吕波[3] 赵涵 何冰[2] WANG Dongxu;XING Chuan;LYU Bo;ZHAO Han;HE Bing(Department of Gastroenterology,Shengjing Hospital of China Medical University,Shenyang 110004,China;Department of Endocrinology,Shengjing Hospital of China Medical University,Shenyang 110004,China;Department of Endocrinology,The Third People’s Hospital of Dalian,Dalian,Liaoning 116033,China)

机构地区：[1]中国医科大学附属盛京医院消化内科,沈阳110004 [2]中国医科大学附属盛京医院内分泌科,沈阳110004 [3]大连市第三人民医院内分泌科,辽宁大连116033

出　　处：《临床肝胆病杂志》2021年第10期2474-2477,共4页Journal of Clinical Hepatology

基　　金：国家自然科学基金(81570765)。

摘　　要：多囊卵巢综合征(PCOS)可表现为生殖、内分泌、代谢等多种紊乱,其中非酒精性脂肪性肝病(NAFLD)的患病率在PCOS人群中显著增高,目前对于PCOS合并NAFLD的危险因素未完全阐明。从高雄激素血症、胰岛素抵抗、肥胖、血脂异常、慢性低度炎症及肠道菌群失调等方面介绍了PCOS合并NAFLD的研究进展,为提高对PCOS合并NAFLD的重视与管理提供思路与方法。Polycystic ovary syndrome(PCOS)manifests as a series of disorders in reproductive system,endocrine,and metabolism,and there is a significant increase in the prevalence rate of nonalcoholic fatty liver disease(NAFLD)in the population with PCOS.At present,the risk factors for PCOS with NAFLD have not been fully clarified.This article introduces the research advances in PCOS with NAFLD from the aspects of hyperandrogenism,insulin resistance,obesity,dyslipidemia,chronic low-grade inflammation,and intestinal flora imbalance,so as to provide ideas and methods for improving the awareness and management of PCOS with NAFLD.

关 键 词：非酒精性脂肪性肝病 多囊卵巢综合征 危险因素 

分 类 号：R575.5[医药卫生—消化系统]