光学相干断层扫描观察特发性黄斑裂孔患者手术前后黄斑区视网膜及脉络膜血流变化  

The application of optical coherence tomography in observation of the circulation of the choroid with the idiopathic macular hole

作　　者：王文娟[1] 王舒怡 张纤 朱宇东 李青[1] 臧晶[1] 徐哲 鲍炯琳[1] WANG Wen-juan;WANG Shu-yi;ZHANG Qian;ZHU Yu-dong;LI Qing;ZANG Jing;XU Zhe;BAO Jiong-lin(Department of Ophthalmology,the First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou 510080,Guangdong,China)

机构地区：[1]广东药科大学附属第一医院眼科,广东广州510080

出　　处：《广东医学》2021年第10期1215-1218,共4页Guangdong Medical Journal

摘　　要：目的对比分析特发性黄斑裂孔(IMH)患者手术前后的视网膜及脉络膜血流变化。方法回顾性分析42例单眼IMH患者,分为患眼组、对侧眼健眼组。应用光学相干断层扫描相关技术(OCT)测量患眼视网膜外层血流面积(ORBFA)、脉络膜毛细血管层血流面积(CBFA)和黄斑中心凹下脉络膜厚度(SFCT),比较手术前后变化。结果术前患眼组的ORBFA为(0.30±0.18)mm^(2),CBFA为(1.54±0.22)mm^(2),SFCT为(221.00±67.99)μm;对侧眼健眼组为ORBFA为(0.90±0.45)mm^(2),CBFA为(1.96±0.21)mm^(2),SFCT为(250.44±57.53)μm。ORBFA和CBFA组间比较差异有统计学意义(P<0.05),而SFCT两组比较差异无统计学意义(P>0.05)。患眼术后ORBFA:(0.92±0.17)mm^(2),CBFA:(1.91±0.17)mm^(2),SFCT:(252.00±57.58)μm。黄斑裂孔术后,ORBFA、CBFA、SFCT均增加,差异有统计学意义(P<0.05)。结论IMH患眼ORBFA和CBFA减少,手术修复后均增加,提示脉络膜循环降低可能是IMH形成的原因。Objective To analyze and quantify the circulation of the choroid and retina in eyes of patients with idiopathic macular hole(IMH).Methods The retrospective study on forty-two patients with unilateral IMH was conducted.The outer retinal blood flow area(ORBFA),the choriocapillary blood flow area(CBFA)and subfoveal choroidal thickness(SFCT)were detected by optical coherence tomography(OCT).The differences of ORBFA,CBFA and SFCT after surgery in groups were analyzed.Results The ORBFA was(0.30±0.18)mm^(2),CBFA was(1.54±0.22)mm^(2),and SFCT was(221.00±67.99)μm in Group Affected eyes before the surgery.And in the unaffected eyes,the ORBFA was(0.90±0.45)mm^(2),CBFA was(1.96±0.21)mm^(2)and SFCT was(250.44±57.53)μm.There were significant differences in ORBFA and CBFA between the 2 groups.After surgery,the ORBFA,CBFA and SFCT of the affected eyes were(0.92±0.17)mm^(2),(1.91±0.17)mm^(2)and(252.00±57.58)μm,respectively;which were all significantly increased than those before surgery(P<0.05).Conclusion The ORBFA and CBFA are both reduced in the affected eyes of IMH,and increased after surgical repairment.This suggests role of the circulation of the choroid in the pathogenesis of IMH.

关 键 词：特发性黄斑裂孔 视网膜外层血流面积 脉络膜厚度 脉络膜毛细血管血流面积 体层摄影术 光学相干 

分 类 号：R774[医药卫生—眼科] R770.41[医药卫生—临床医学]